RED CELL DISTRIBUTION WIDTH AS A MARKER OF PREECLAMPSIA SEVERITY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 48
Abstract
BACKGROUND Red cell distribution width, used traditionally to differentiate various types of anaemia is also documented to be associated with severity of hypertension in non-pregnant population. However, there is scarcity of its usefulness in hypertensive disorders of pregnancy. This study was undertaken to examine the role of red cell distribution width in predicting the severity of preeclampsia. MATERIAL AND METHODS One hundred and forty three patients of preeclampsia and nine hundred and eleven normal pregnancy cases were included in the study during a period of one year. The severity of preeclampsia was classified as mild (n=76) or severe (n=67). RESULTS Red cell distribution width was significantly higher in severe preeclampsia group (p<0.001). It was positively correlating with mean arterial pressure with r=0.343; p<0.001. Receiver operating characteristic curve analysis showed area under curve of 0.766, 95% Confidence Interval (CI) 0.70-0.83. Cut off value of >15.9% was found to have significant value for differentiating mild and severe forms of preeclampsia. CONCLUSION Red cell distribution width is associated with preeclampsia and has a good diagnostic significance in severe preeclampsia.
Authors and Affiliations
Shilpa Reddy, Harendra , Geetanjali , Pushpa Kottur
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