ROLE OF MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF ADULT ONSET MOVEMENT DISORDERS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 26
Abstract
BACKGROUND Magnetic Resonance Imaging (MRI) is an important tool in distinguishing between the types of movement disorders based on characteristic patterns of regional atrophy, signal changes or microstructural changes in basal ganglia, pons, midbrain, middle and superior cerebellar peduncles and cerebral subcortical white matter. Combination of various imaging features and clinical features are helpful for better diagnosis in movement disorders. So the purpose of this study is to characterise all movement disorders diagnosed by clinical examination using conventional MRI techniques and to evaluate MRI features of various conditions presenting as movement disorders. METHODS 50 patients with clinically diagnosed central cause of movement disorders were included in this study. Patterns of atrophy and signal distribution were studied in patients with Parkinson’s disease, atypical Parkinson’s disease, Wilsons’s disease, ataxia, chorea, dystonia and myoclonic jerks; 1.5 Tesla General electrical Medical systems MRI Brain T1, T2 and FLAIR (Fluid attenuation inversion recovery) AXIALS, Spoiled Gradient (SPGR) volumetric data with 2 mm thick coronals and GR (Gradient) axials were studied. RESULTS 50% of clinically diagnosed movement disorders are of Parkinson’s disease. Diffuse cerebral atrophy and periventricular signal changes are the most common MR finding seen. Routine MRI is highly accurate in case of high clinical suspicion of the Wilson’s and least accurate in Parkinson’s disease and Atypical Parkinson’s Diseases (APD). CONCLUSIONS MRI findings are never diagnostic in themselves, but taken in the context of the clinical picture can point the way to the correct diagnosis
Authors and Affiliations
Padmaja , Nageswara Tummala, Haritha , Afsar Shaik, Rajeswara Tummala
Keywords
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- EP ID EP118112
- DOI 10.14260/jemds/2016/320
- Views 102
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