Selective extraction of berberine and palmatine from Huangbai powder
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2013, Vol 26, Issue 5
Abstract
Berberine and palmatine are two of the main bioactive components in Huangbai, a major Chinese medicinal herb. The current methods to extract these compounds usually involving the usage of inorganic acid and base, are not only complex and time-consuming, but have a low selectivity. In this paper, it was reported that hexane, ethyl acetate and dichloromethane were tested to extract berberine and palmatine from Huangbai powder. The results showed that dichloromethane extracted selectively and effectively berberine and palmatine from Huangbai powder among the examined solvents. In addition, dichloromethane can be recycled and reused, making it a potential candidate for large scale extraction of berberine and palmatine from Huangbai.
Authors and Affiliations
Cunliu Zhou, Jun Li, Shengjiang Tan, Huiqiong Ye
Keywords
Related Articles
- EP ID EP93502
- DOI -
- Views 106
- Downloads 0
Molecular mechanisms that underlie the sexual stimulant actions of Avicennia marina and Crocus sativus
The effects of extracts and sub-fractions of Avicennia marina, Crocus sativus and sildenafil on the sexual behavior of male rats and their effects on the intracavernosal pressure (I.CV), intracavernosal cyclic GMP...
Research progress of the studies on the roots of Peucedanum praeruptorum dunn (Peucedani radix)
As a commonly employed traditional Chinese medicine, Peucedani Radix (Qian-hu in Chinese), which consists of the dried roots of Peucedanum praeruptorum Dunn, has a long history of application for the treatment of c...
Influence of Artemisia annua extract derivatives on Proliferation, apoptosis and metastasis of osteosarcoma cells
Regarding the Artemisia annua extract derivatives called dihydroarteminin (DHA) as the object, we studied about its influence to the proliferation, apoptosis and metastasis of human osteosarcoma cells. First, we cu...
Effects of intravenous bolus injection of emulsified isoflurane on QTc interval of healthy volunteers in Pharmacokinetics study
Emulsified isoflurane is a novel intravenous anesthetic, which is a lipid emulsion of isoflurane. As some drugs have a QTc-prolongation effect which can increase a risk of arrhythmia, this study was to evaluate the...
Phytochemicals, in vitro antioxidant, total phenolic contents and phytotoxic activity of Cornus macrophylla Wall bark collected from the North-West of Pakistan
Plants are one of the precious creatures of Allah, producing a verity of useful bioactive compounds having definite pharmacological actions on human body. Keeping in view this idea, the methanolic extract from the...