Significance of Serum Uric Acid Level in Patients of Stroke with Diabetes Mellitus
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2014, Vol 4, Issue 1
Abstract
[b] INTRODUCTION:[/b] Some studies have linked serum uric acid with stroke in diabetes mellitus. But it is debated. Therefore, we propose to evaluate hyperuricemia as a risk factor for stroke in patients with diabetes mellitus. [b]METHODS:[/b]In this cross-sectional observational study we studied 100 patients of stroke (both ischemic and hemorrhagic) with diabetes mellitus and compared with 50 controls of stroke (both ischemic and hemorrhagic) without diabetes mellitus and 50 patients of diabetes mellitus without stroke, serum uric acid levels were measured and compared using chi-square test, ANOVA, regression analysis by standard biomedical software (SPSS version 20). [b]RESULT:[/b] In this age and sex matched study the mean uric acid level was highest in diabetic stroke patients (7.98±1.77mg/dl) compared to non-diabetic stroke patients (6.34±1.51mg/dl) and it was lowest in only diabetic patients (5.96±1.50mg/dl; p value <0.001). And, the serum level of uric acid is significantly correlated with FBS, PPBS, glycated haemoglobin, and with duration of diabetes (p value <0.05). [b]CONCLUSION: [/b]In conclusion high serum uric acid level is associated with stroke patients with diabetes mellitus and also well correlated with blood glucose levels and duration of diabetes. So, hyperuricemia may be used as a marker of stroke with diabetes, further and larger study is needed to conclude that.
Authors and Affiliations
Tanmoy W Momin , Pijush K Mandal
Keywords
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