Spectrophotometric Determination of Cardiovascular Drugs
Journal Title: International Journal of Modern Engineering Research (IJMER) - Year 2013, Vol 3, Issue 5
Abstract
Simple, sensitive, accurate and precise spectrophotometric methods for quantitative determination of cardiovascular drugs viz., Dobutamine Hydrochloride (DOB), Ramipril (RAM), Telmisartan (TEL), Verapamil Hydrochloride (VER) were developed. The method of each drug depends upon oxidation of drugs by Ce (IV) (Excess) and estimating the amount of un reacted Ce (IV) by amaranth dye at 523nm. The calibration curves obeyed Beer’s law over the concentration range of 1.6-12µg ml-1(DOB), 8-56 µg ml-1(RAM), 2-14 µg ml-1(TEL) & 2-12 µg ml-1(VER). The method has been validated in terms of guidelines of ICH and has been applied to analysis of pharmaceuticals.
Authors and Affiliations
K. Sayanna, G. Venkateshwarlu
Keywords
Related Articles
- EP ID EP88092
- DOI -
- Views 117
- Downloads 0
An Efficient top- k Query Processing in Distributed Wireless Sensor Networks
Wireless Sensor Networks (WSNs) are usually defined as large-scale, ad-hoc, multi-hop and wireless unpartitioned networks of homogeneous, small, static nodes deployed in an area of interest. Applications of sensor networ...
Potentials Of and the Socio-Economic Benefits of Blacksmithing Production in Promoting Agricultural Development and Poverty Alleviation in Kwara State, Nigeria
Agriculture and technological development including blacksmithing promotes agricultural tools production and offers an unexploited succor capable of salvaging the people from abject poverty. Blacksmithing and its product...
The Mechanical Behaviour of Recycled High Density Polyethylene
Abstract: In last few years with the increasing use of polymeric materials the disposal of the used material became a serious problem. As polyethylene is one of the common used polymers in many applications it repr...
UPFC in order to Enhance the Power System Reliability
The maintenance and reliability of the power system has become a major aspect of study. The solution is the use of FACTS devices especially the use of UPFC. Unified Power Flow Controller (UPFC) is the most widely use...
Analyzing the indicators Workability of cities, in order to improving urban vitality
Urban design is a technique and knowledge seeking to organize and improve urban qualities and increase the quality of citizenship life. Based on the perspectives and objectives of urban design, the dominant intention in...