Spectroscopic analysis on Synthesis 1-Methyl-3-(2’-Phenylethyl)- 1H,3H-Quinazoline-2,4-dione
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2014, Vol 4, Issue 2
Abstract
Carbomethoxy-methylanthranilic acid was synthesized from methylanthranilic acid with methylchloroformate in presence of potassium carbonate. Cyclisationreaction of Ncarbomethoxymethylanthranilic acid was performed by heating to get N-methylisatoic anhydride. 2- metholamino-N-(2’-phenylethyl) benzamidewas formed from Isatoic anhydride and phenylethyl amine. High yield of 1-methyl-3-(2’- phenylethyl)-1H,3H-quinazoline-2,4-dione alkaloids were formed by condensation and cyclisation reaction between amide and methylchloroformate. The synthesis compound was identified with the help of its melting point, C 13 NMR and H 1 NMR spectra.
Authors and Affiliations
Sushika Joshi (Mulmi)
Keywords
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