Staphylococcal resistance against five groups of life saving antibiotics in the year 2003-2005
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2013, Vol 26, Issue 6
Abstract
In the year 2003 to 2005 a prospective study was conducted to find out the predominance of Staphylococcus (Staphylococcus aureus) resistance pattern in opposition to five life saving antibiotics as these are the sole agents to treat critically ill patients in hospitals. During the period of two years almost 2500 samples of bacterial culture were taken from different pathological laboratories and hospitals in Karachi. Among these 1500 were Gram positive cocci and 1000 samples were identified as Staphylococcus aureus. Life saving antibiotics were taken from five different groups and by mean of disk diffusion technique antibiogram of Staphylococcus aureus against these antibiotic were determined. During the course of study imipenem showed 11%, amikacin exhibited 58%, cefipime showed 31%, vancomycin and piperacillin/tazobactam displayed 24% resistance against Staphylococcus aureus. Imipenem was found to be most effective against Staphylococcus aureus.Resistance to other antibiotics developed quickly in Staphylococcus aureus collected from clinical areas where these antimicrobial agents are extensively used.
Authors and Affiliations
Anab Fatima , Syed Baqir Shyum Naqvi , Sheikh Abdul Khaliq , Shaheen Perveen , Rabia Ismail Yousuf , Rehana Saeed
Keywords
Related Articles
- EP ID EP109800
- DOI -
- Views 90
- Downloads 0
Latex agglutination: Diagnose the early cryptococcus neoformans test of capsular polysaccharide antigen
This paper aims to discuss the early diagnosis value of latex agglutination test in Cryptococcal meningitis. The cerebrospinal fluid (CSF) of 112 patients with definite Cryptococcal meningitis and 26 patients with...
Screening and optimization of some inorganic salts for the production of ergot alkaloids from Penicillium species using surface culture fermentation process
The present study deals with the production of ergot alkaloids from Penicillium commune and Penicillium citrinum, using surface culture fermentation process. Impact of various inorganic salts was tested on the prod...
[u][/u] Preliminary evaluation of antimicrobial activity of cream formulated with essential oil of Trachyuspermum ammi
: In our present research we studied physiochemical properties and antimicrobial activity of T. ammi (Trachyuspermum ammi) seeds. The seeds yielded 2.86% essential oil. Refractive index, specific gravity, acid valu...
Nano-liposomes of entrapment lidocaine hydrochloride on in vitro permeability of narcotic
In order to explore two kinds of nano-liposomes in lidocaine hydrochloride nano-liposomes on in vitro permeability of drug, and conduct comparison and analysis, this paper investigates cumulative infiltration situa...
Development and formulation of metformin (Antidiabetic) effervescent Granules: To increase patient compliance and its stability study
Convenience of administration and patient compliance are gaining importance in the formulation of dosage forms. Many patients, like elderly people and person with dysphagia find difficulty to swallow the tablets an...