THE RATE OF TUBERCULOSIS INFECTION IN HIV POSITIVE PATIENTS IN RELATION TO CD4 COUNT
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 21
Abstract
[b] INTRODUCTION[/b]: Tuberculosis is the most common HIV-related opportunistic infection in India, and caring for patients with both diseases is a major public health challenge, which places an immense burden on health care systems and poses particular diagnostic and therapeutic challenges, increasing the risk of treatment failure, relapse and death. Estimates by the World Health Organization (WHO) indicate that there are more than 9 million new active cases of TB and close to 2 million deaths per year. [b]MATERIALS AND METHOD[/b]: The present retrospective study was conducted for a period of one year. HIV status was confirmed for patients attending voluntary counselling and testing centre (VCTC). HIV positive patients were referred to designated microscopic centre (DMC) for sputum examination for AFB and ART centre for estimation of CD4 count and necessary relevant investigations were carried out for extrapulmonary tuberculosis (EPTB). [b]RESULTS[/b]: Out of 682 HIV positive patients, 93(13.6%) cases were diagnosed with pulmonary tuberculosis. Extrapulmonary tuberculosis was detected in16 (2.3%) patients. The commonest form of EPTB was cervical adenitis detected in13 (1.9%) of cases and pleural effusion in 3 (0.4%) of cases respectively. The mean CD4 count was 208 cells/µl in patients with pulmonary tuberculosis (PTB) and 192cells /µl , 162 cells /µl in patients with cervical adenitis and pleural effusion. [b]CONCLUSIONS[/b]: Further reduction of CD4 count occurs in dually infected patients. Early diagnosis and prompt institution of ART and ATT reduces mortality and morbidity significantly.
Authors and Affiliations
Sreekanth B, Chakraverti T. K, Saileela K, Sateesh K, Ravi Reddy, Lakshmivasantha P
Keywords
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- EP ID EP111853
- DOI 10.14260/jemds/759
- Views 91
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