TREND OF HEPATITIS B AND HEPATITIS C INFECTIONS IN A TERTIARY CARE MEDICAL INSTITUTE IN EASTERN INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 35
Abstract
BACKGROUND In Manipur, one of the six high HIV-prevalence states of India, information is limited regarding Hepatitis B and C infections, which share a similar parenteral mode of transmission. AIMS To investigate the trend of Hepatitis B surface antigen (HBsAg) and Hepatitis C antibodies (HCVAb) and to identify the seropositivity rates at different age-groups. SETTING & DESIGN A retrospective cross-sectional study was conducted at the Microbiology Department of a Tertiary Care Medical Institute on existing data from 2010-2015. MATERIALS & METHODS Serum samples were screened for HBsAg and HCVAb using rapid immunochromatography tests and 3rd generation enzymelinked immunosorbent assays (ELISA). STATISTICAL ANALYSIS The prevalence of both hepatitis B and C infections were analysed by using Student’s t-test at probability level of 5%. A P-value of less than or equal to 0.05 was considered statistically significant. RESULTS The data of 37352 serum samples were collected. 250 (2.4%) and 552 (5.4%) of 10121 males were positive for HBsAg and HCVAb respectively, and 132 (0.8%) and 78 (0.5%) of 16568 females were positive for HBsAg and HCVAb respectively. 43 (0.42%) males and 12 (0.04%) females were positive for both infections. For HBsAg, the yearly seroprevalence ranged from 1.55 to 4.2% among the males and from 0.66 to 1% among the females. For HCVAb, it ranged from 3.91 to 8.17% among the males and from 0.30 to 0.64% among the females. Difference in seroprevalence between males and females were found to be statistically significant at P-value <0.05. Seropositivity rates were maximum at 41-50 years for both infections among positive males, and at 21- 30 years for HBsAg and 31-40 years for HCVAb among positive females. CONCLUSION The rising seroprevalence rates of both hepatitis infections, especially those of HCV infection among the males need urgent attention.
Authors and Affiliations
Supriya , Gurumayum , Vyas
Keywords
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- EP ID EP112582
- DOI 10.14260/jemds/2016/483
- Views 63
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