NECROLYTIC ACRAL ERYTHEMA: HIGH DEGREE OF SUSPICION FOR DIAGNOSIS
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2015, Vol 4, Issue 2
Abstract
Necrolytic Acral Erythema (NAE) is a recently described, poorly understood, rare dermatological entity, which is frequently associated with Hepatitis C Virus (HCV) infection. This report describes a 53 year old male with a 6 month history of well demarcated, reddish brown to hyperpigmented, scaly skin over dorsum of both hands and feet. Investigations revealed hypothyroidism and low serum zinc levels. Patient also tested seropositive for HCV. Histopathological examination revealed hyperkeratosis and subcorneal clefting along with areas of necrosis. Patient was started on oral zinc along with treatment for hypothyroidism, and improved symptomatically in 2 weeks. Early recognition of NAE is of prime importance to dermatologists as it allows diagnosis of HCV in previously unaware patients and gives way for efficacious treatment.
Authors and Affiliations
Shumez H | Junior Resident, Department of Dermatology, Venerology and Leprosy, Annamalai University, Tamil Nadu, India, Corresponding author email: shumezh@gmail.com, Prasad PVS | Professor, Department of Dermatology, Venerology and Leprosy, Annamalai University, Tamil Nadu, India, Kaviarasan PK| Professor & Head, Department of Dermatology, Venerology and Leprosy, Annamalai University, Tamil Nadu, India, Viswanathan P| Professor & Head, Department of Pathology, Rajah Muthiah Medical College and Hospital, Annamalai University, Tamil Nadu, India
Keywords
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- EP ID EP11414
- DOI 10.5958/2319-5886.2015.00080.6
- Views 280
- Downloads 12
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