Necrotizing Enterocolitis with Perforation in Neonates: Primary Peritoneal Drainage Irrespective of Birth Weight Resulting in Improved Survival

Journal Title: New Indian Journal of Surgery - Year 2017, Vol 8, Issue 2

Abstract

Background: Necrotizing enterocolitis (NEC) is the most common life threatening emergency of the gastrointestinal tract in newborn period. Despite aggressive medical management many patients develop complications which require surgical intervention. There is controversy regarding the optimal timing and type of surgical intervention in these high risk patients. This paper presents our experience of peritoneal drainage as the primary treatment in all patients of NEC with bowel perforation and its effect on the overall survival of these patients. Method: Total 142 patients of NEC with perforation were admitted in the study period of 5 years. These patients were prospectively analysed. Patients were divided in two groups according to their body weight to judge the clinical improvement by the peritoneal drainage (Group 1- birth weight< 1500 grams, and group 2- birth weight > 1500 grams). All these patients of NEC (irrespective of their weight and gestational age) with perforation were subjected to primary peritoneal drainage. Results: Primary peritoneal drainage (PPD) provided a cure in more than half of these high risk babies. Out of 142, 80 patients required no other operative procedure and they were considered cured by PPD only. The survival was 61.7% in group 1 while group 2 had a survival rate of 68.9%. Conclusion: The study shows that, though the primary peritoneal drainage is not a definitive cure in patients of NEC with perforation, but it definitively reduces the number of laparotomies and also helps in improving the general condition of the patients who need surgery later on. Primary peritoneal drainage (PPD) reduces the mortality in these high risk neonates.

Authors and Affiliations

Tanvir Roshan Khan

Keywords

Related Articles

Usefulness of Mannheim’s Peritonitis Index Screening System in Predicting Outcome in Patients with Peritonitis

“Peritonitis is an inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs. Peritonitis may be localized or generalized, and may result from infect...

Retrospective and Prospective Study of Modified Asopa-I Repair in Hypospadias Patients

Context: There is no data published on the outcome and complications of Modified Asopa-I repair, though it is conceptually proved to be superior and results are better. Hence study on this subject was necessary. Aims: To...

A Clinical Study of 50 Patients of Cellulitis Treated in our Hospital

Cellulitis is an inflammation of skin and subcutaneous tissue following a trivial trauma to the skin. Lower limb cellulitis is the commonest site for this inflammation. Cellulitis can occur anywhere on the body, but is m...

A Clinical Profile of Acute Intestinal Obstruction Cases at Tertiary Care Hospital

Introduction: Mortality and morbidity are dependent on early recognition and correct diagnosis of obstruction. If untreated, strangulated obstruction causes death in 100% of patients. If surgery is performed within 36 ho...

Shahaji Chavana, Omkar Mahendra Shirkeb, Balaji Dhaigudec, (Col) S.V. Panchbhaid, Gaurav Batrae

Introduction: Necrotizing fasciitis represents a group of highly lethal infections characterized by rapidly progressing inflammation & necrosis. Early recognition & aggressive surgical treatment in combination with antib...

Download PDF file
  • EP ID EP471538
  • DOI 10.21088/nijs.0976.4747.8217.23
  • Views 98
  • Downloads 0

How To Cite

Tanvir Roshan Khan (2017). Necrotizing Enterocolitis with Perforation in Neonates: Primary Peritoneal Drainage Irrespective of Birth Weight Resulting in Improved Survival. New Indian Journal of Surgery, 8(2), 144-147. https://europub.co.uk/articles/-A-471538