Neonatal positivity of CRP test in early onset neoanatal sepsis in relation to duration of PROM vs PROM delivery Interval (PDI)
Journal Title: IP International Journal of Medical Paediatrics and Oncology - Year 2016, Vol 2, Issue 2
Abstract
Aim: To know, which one, PROM duration or PDI is in high risk for CRP positive early onset neonatal sepsis to start antibiotic in treatment to prevent perinatal morbidity and mortality. Methodology: Total 150 newborn cases admitted to NICU, diagnosed as EONS associated with their maternal history PROM were taken. The information in all the neonate, enrolled into the study as sex, gestational age, weight, with maternal duration of PROM and PROM delivery interval were recorded. In all the cases CRP was done by latex agglutination test and blood culture was sent to confirm sepsis. Results: There were 40% cases of CRP positivity in EONS with 6 hour of PROM in comparison to 63% positivity associated with PDI of 12 hour duration. CRP was positive in all cases that presented beyond 24 hour of rupture of membrane. The risk of developing EONS was higher (100%) in cases that delivered beyond 24 hours of PDI compared to the cases that delivered within 24 hours. There was a statistical significant relationship of CRP with PROM and PDI (P value-<0.05). Conclusion: Preventive measures should focus on recognition of factor according to the risk, such as PROM even if 6 hour is high for neonate, PDI should be considered first, with prompt laboratory screening for sepsis. Early institution of empirical antibiotic in treatment to prevent need for neonatal intensive care without increase in perinatal morbidity and mortality
Authors and Affiliations
Sudhanshu Kumar Das, Monalisa Subudhi, K. B. Subudhi
Keywords
Related Articles
- EP ID EP242887
- DOI -
- Views 150
- Downloads 0
Cyanotic atrial septal defect: Literature review
Atrial septal defects ASD constitute a tenth of all congenital heart disease in children It is a common cause of acyanotic congenital heart defects in children Cyanosis in a case of ASD is something which should hint tha...
Primary cutaneous nocardiosis: case report and review
Background: Infection caused by Nocardia species are uncommon and primary cutaneous nocardiosis is relatively rare. The lymphocutaneous pattern of the disease is the rarest type and commonly occurs in otherwise healthy i...
Developmental Outcome of Nicu Graduate Weighing Less than 2500 Grams in A Tertiary Care Hospital
Background and objective: The early intervention programmes designed for low birth weight babies can be beneficial to improve the prognosis in terms of physical growth and neurodevelopmental outcome. The purpose of this...
Gestational trophoblastic disease (GTD)
Gestational trophoblastic disease comprises hydatidiform mole (complete and partial) and gestational trophoblastic neoplasia. The epidemiology, clinical features, and diagnosis of each of these trophoblastic disease type...
Oral Cancer- A Real Threat to Society
Oral cancers often occurs out of long standing potentially malignant lesions and conditions so called premalignant lesions and conditions. Oral precancer is an intermediate state with increased cancer rate which can be r...