Neonatal sepsis: Changing bacteriological profile, a study in tertiary care NICU in Bihar
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
BACKGROUND:bacteriological profiling is very important as sepsis remains one of major cause of mortality in NICU in Bihar. Changing pattern of bacterial infection and emergence of resistant strains in NICU has posed great challenge before treating paediatricians. This study will look into prevalent strains in NICU and will help in reducing sepsis related mortality and morbidity. MATERIAL AND METHODS: It was across sectional study conducted in NICU of NMCH from November 2017 to April 2018. All patient admitted in NICU during this period with diagnosis of sepsis were included in this study. Blood cultures were sent and report analysed.RESULT:Out of 365 samples 140 (38%) were positive and showed growth. 60% (n=85) were male and female were 40% (n=57). Mean age of admission was 4.2 day. Inborn was 10% (n=14)outborn was 90% (n=127). Premature was 30% (n=42). Low birth weight accounted for 60% (n=84) cases of culture positive sepsis. Most common organism isolated was Staph. aureus(39%) out of which MRSA was36% of total Staph aureus. ESBL accounted for 58% OF gram negative isolates which included Klebsiella(42%), E.coli(33%), NFGO(10%), Enterobacter(14%). All Acinetobacter isolated were MDR.Conclusion:There is shift in prevalence of gram positive organism in NICU. NFGO and Acinetobacterbaumanii which dwell in NICU and spread by cross infection needs to be checked. Urgent and strict action plan is needed at every level of care giving to check the spread of resistant organism.
Authors and Affiliations
Dr. Kumar Arpit, Dr. Akhilesh Kumar, Dr (Prof. ) Alka Singh
Keywords
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- EP ID EP431024
- DOI 10.9790/0853-1801035760.
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