Neonatal Thrombocytopenia in Hospitalised Sick Neonates
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 2
Abstract
Thrombocytopenia is one of the common hematological problem encountered in the neonates admitted in NICU and usually indicate an underlying pathologic process. A retrospective review, of case papers of neonates admitted at tertiary level NICU of Govt. medical college Kota from oct. 2012 to sept. 2013,was done to determine the number of cases and manifestations of thrombocytopenia in sick neonates. A total 2256 neonates were included in study, were evaluated for thrombocytopenia. These neonates were categorized into five different groups (A, B, C, D, E), which were of neonatal sepsis, birth asphyxia, preterm and low birth weight, neonatal jaundice and miscellaneous respectively. Out of 2256 cases, 516 (22.87%) had thrombocytopenia (platelet counts < 150,000 / mm3 ). In group A (neonatal sepsis), out of 696 neonates, 224 (32.18%)) had thrombocytopenia. In group B (birth asphyxia), out of 468 cases, 136 (29.1%) had thrombocytopenia. In group C (preterm and low birth weight), out of 552 cases 132(23.9%) had thrombocytopenia. In group D (neonatal jaundice), out of 252 cases 12(4.7%) cases had thrombocytopenia. In group E (miscellaneous), out of 288cases, only 24 (8.33%) had thrombocytopenia. The common manifestations were petechiae and bruises followed by G.I. hemorrhages and intracranial hemorrhages. The percentage of manifest thrombocytopenia cases was 48.34%. The leading causes of thrombocytopenia in sick neonates are congenital or acquired infections, sepsis, , birth asphyxia, , complicated prematurity and low birth weight. all immune thrombocytopenia Severe thrombocytopenia may be associated with increased risk of hemorrhage, and increased mortality.
Authors and Affiliations
Dr Dipendra Sharma
Keywords
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