NEPHROGENIC SYSTEMIC FIBROSIS: A HIGHLY RELEVANT AND SIGNIFICANT ADVERSE EFFECT ASSOCIATED WITH GADOLINIUM BASED MRI CONTRAST AGENTS
Journal Title: World Journal of Pharmaceutical and Medical Research - Year 2017, Vol 3, Issue 8
Abstract
Nephrogenic systemic fibrosis (NSF), also known as nephrogenic fibrosing dermopathy (NFD), is a disease of fibrosis of the skin and internal organs reminiscent but distinct from scleroderma or scleromyxedema. It is caused by gadolinium exposure used in imaging in patients who have renal insufficiency. Nephrogenic systemic fibrosis always occurs in patients with renal insufficiency who have had imaging studies (eg, magnetic resonance angiography) with gadolinium, a contrast agent used in imaging studies. Nephrogenic systemic fibrosis resembles scleroderma and eosinophilic fasciitis clinically and scleromyxedema histopathologically. Patients with nephrogenic systemic fibrosis may develop large areas of indurated skin with fibrotic nodules and plaques. Flexion contractures with an accompanying limitation of range of motion also can occur.
Authors and Affiliations
Dr. Poonam Vohra
Keywords
Related Articles
- EP ID EP657321
- DOI -
- Views 178
- Downloads 0
PLEOMORPHIC ADENOMA AS NASAL MASS: A RARE CASE REPORT
Pleomorphic adenoma is the most common benign tumor of the major salivary glands with highest incidence in the parotid gland. They may also be seen arising from the minor salivary glands present in the upper aerodigestiv...
ROLE OF SOME UNANI SINGLE DRUGS IN THE TREATMENT OF DIABETES MELLITUS TYPE- 2: A REVIEW
The term diabetes mellitus (DM) describes a metabolic disorder of multiple aetiology, characterized by chronic hyperglycaemia with disturbance of carbohydrate, fat and protein metabolism; resulting from defects in insuli...
INCIDENTALLY DIAGNOSED HYDATID CYST - A CASE REPORT
Hydatid disease, caused by the parasite Echinococcus granulosus, mostly affects the liver and the lungs with hydatid cysts which consist of three layers: (1) the outer pericyst; (2) the middle laminated membrane; and (3)...
INVESTIGATIONS ON INTESTINAL AMOEBA USING VARIOUS LABORATORY DIAGNOSTIC METHODS AMONG STUDENTS IN KOSTI CITY, WHITE NILE STATE SUDAN
Two hundred stool samples were collected from four basic school children in Kosti city, Kosti Province, White Nile State and examined to assess the use of poly vinyl alcohol (P.V.A) in smears prepared from Balamuth’s med...
CONCEPT OF MEDICAL NEGLIGENCE IN AYUEVEDA AND MODERN ASPECTS
Negligency is an issue of serious human right concern that directly affects right of life and right to health care. Healthcare practice has increased so much that the public expectation regarding safety is racing ahead....