Network Pharmacology and Traditional Chinese Medicine: Development of Anti-Diabetic Therapies
Journal Title: International Journal of Diabetes and Clinical Research - Year 2017, Vol 4, Issue 2
Abstract
Partly due to the failure of single-target drugs, diabetes mellitus, a chronic metabolic disease with complex pathogenesis and long-term medication requirements, is increasing in prevalence worldwide and urgently needs multi-component and multi-target treatments. Traditional Chinese herbs are the principal drug of Chinese medicine, which is effective against diabetes. However, Chinese herbs' mechanism of action is difficult to elucidate due to its multiple components and multi-target effects. Based on the theories of systems biology and biological network equilibrium, network pharmacology could be applied to study disease mechanism and drug efficacy. This review postulates that network pharmacology may play a key role in revealing the anti-diabetic mechanism of Traditional Chinese Medicine (TCM) and will have potential effects on the modernization of TCM.
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- EP ID EP350599
- DOI 10.23937/2377-3634/1410077
- Views 113
- Downloads 0
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