Neurogenic inflammation markers in children with vertebrobasilar arterial system syndrome and recurrent bronchitis

Journal Title: Здоров`я дитини - Year 2017, Vol 12, Issue 4

Abstract

Background. The study of the neurogenic maintenance characteristics of the recurrent bronchitis (RB) course in children with the vertebrobasilar arterial system syndrome (VBASS) by studying the levels of the final stable metabolites of nitric oxide (FSM NO), substance P and vasoactive intestinal peptide (VIP) will make it possible to establish important elements of the frequent diseases respiratory tract pathogenesis. Materials and methods. Sixty children aged 7 to 11 years old with anamnesis of RB were examined. Two observation groups were formed (30 patients in each): 1) children with RB in the period of somatic well-being and VBASS; 2) children with RB in the period of somatic well-being without VBASS. Results. In children with RB, who have VBASS, as compared to the children without VBASS, we have detected an increase in FSM NO serum levels (by 36.7 %, p < 0.05) (odds ratio (OR) = 6.50, 95% confidence interval (CI) 1.82–23.21, p < 0.05), substance P (by 40.0 %, p < 0.05) (OR = 6.00, 95% CI 1.89–19.04, p < 0.05), a decrease in concentration of VIP (by 26.7 %, p < 0.05) (OR = 3.05, 95% CI 1.05–8.84, p < 0.05) statistically significantly more often. Conclusions. In children with RB and VBASS, during the period of somatic well-being, the focus of the neurogenic inflammatory process takes place, which is accompanied by an autonomous neuronal processes imbalance and predisposition to recurrent bronchopulmonary pathology.

Authors and Affiliations

L. S. Ovcharenko, T. V. Slutskaya

Keywords

Related Articles

The Place of Probiotics in the Treatment and Prevention of Secondary Acetonemic Syndrome

The article deals with the problem of therapy for acetonemic syndrome in children with acute respiratory viral infections. Application of probiotic preparation Subalin in the treatment of secondary acetonemic syndrome is...

Health status of young athletes — pupils of the school of physical culture

Background. Health status of young athletes — pupils of the schools of physical culture — remains unexplored. The purpose of the study was a comparative assessment of health status of young athletes, depending on their a...

Metabolic therapy in children with hypotensive type of autonomic dysfunction syndrome

Background. Trimetabol is a combined appetite stimulant that has cardioprotective, neurotropic and antioxidant effects. The purpose was to evaluate the effectiveness of metabolic therapy with the use of Trimetabol in chi...

Peculiarities of venous hemodynamics of the brain in children with asthma

Background. Data on the number of patients with chronic cerebral ischemia among children and adolescents are single and small. Consequently, the relevance of the study of the state and changes in cerebral hemodynamics, i...

About Insipidus Syndrome in Pediatric Practice

The article presents the data on the etiology, pathogenesis, clinical picture and differential diagnosis of insipidus syndrome. The own clinical observation of nephrogenic diabetes insipidus in 17-year-old boy is describ...

Download PDF file
  • EP ID EP213391
  • DOI 10.22141/2224-0551.12.4.2017.107627
  • Views 83
  • Downloads 0

How To Cite

L. S. Ovcharenko, T. V. Slutskaya (2017). Neurogenic inflammation markers in children with vertebrobasilar arterial system syndrome and recurrent bronchitis. Здоров`я дитини, 12(4), 465-468. https://europub.co.uk/articles/-A-213391