Neuroimage of the Subventricular Zone Associated with Intrauterine Ischemic Infarction
Journal Title: Imaging Journal of Clinical and Medical Sciences - Year 2016, Vol 3, Issue 1
Abstract
Introduction. Recent studies that characterize the subventricular zone (SVZ) have identified the role that it represents for neurogenesis, neuromigration processes and the formation of cortical neural networks. There are two neurogenic niches in the adult human brain, the SVZ and the dentate gyrus of the hippocampus, where neural stem cells have a significant potential of differentiation to become glial cells and neurons. Alterations resulting from structural lesions affecting the human SVZ may represent neurodevelopment disorders. Methods. We present a case about a 5 year-old male child that had an intrauterine stroke, presenting hypoactivity and secondarily generalized partial seizures at birth. The nuclear magnetic resonance imaging demonstrates a delimitated area between the encephalomalacia area and the ex-vacuo ventricular dilatation that corresponds to the ventricular wall, which highlights an important transitional component of the subventricular zone. Result. The present case contributes to the evidence of the failure in cortical formation when the precise migrating mechanism from the SVZ is not correctly developed. Conclusion. New technologies will allow to set up anatomo-functional correlations of the SVZ and to establish potential links with neurodevelopmental pathologies associated with a primary lesion.
Authors and Affiliations
Ramos-Zuñiga R, Rochin-Mozqueda JA, García-Mercado CJ
Keywords
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- EP ID EP348600
- DOI 10.17352/2455-8702.000028
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