Neuropharmacological effects of Albizzia Chinensis extract
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2018, Vol 5, Issue 3
Abstract
Introduction To know the Neuropharmacological effects of Albizzia chinensis extract in rats and miceMaterials and Methods The test compound was evaluated experimentally for its neuropharmacological activities in rats and mice Blind neuropharmacological screening potentiation of barbiturate hypnosis stimulation of the central nervous system maximal electroshock and pentylenetetrazol induced convulsions analgesic activity were studiedResults The compound potentiated pentobarbital hypnosis reduced spontaneous motor activity antagonized amphetamine induced hyperactivity blocked the conditioned avoidance response without affecting the unconditioned response and showed analgesic activity by the tailflick method but not in hot plate model in the experimental animalsConclusion The compound is similar to chlorpromazine and morphine Keyword Saponin Central nervous system Animals
Authors and Affiliations
Dinesh Kansal, Naresh Gupta
Keywords
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- EP ID EP478559
- DOI 10.18231/2393-9087.2018.0028
- Views 87
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