Neuropharmacological effects of Albizzia Chinensis extract
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2018, Vol 5, Issue 3
Abstract
Introduction To know the Neuropharmacological effects of Albizzia chinensis extract in rats and miceMaterials and Methods The test compound was evaluated experimentally for its neuropharmacological activities in rats and mice Blind neuropharmacological screening potentiation of barbiturate hypnosis stimulation of the central nervous system maximal electroshock and pentylenetetrazol induced convulsions analgesic activity were studiedResults The compound potentiated pentobarbital hypnosis reduced spontaneous motor activity antagonized amphetamine induced hyperactivity blocked the conditioned avoidance response without affecting the unconditioned response and showed analgesic activity by the tailflick method but not in hot plate model in the experimental animalsConclusion The compound is similar to chlorpromazine and morphine Keyword Saponin Central nervous system Animals
Authors and Affiliations
Dinesh Kansal, Naresh Gupta
Keywords
Related Articles
- EP ID EP478559
- DOI 10.18231/2393-9087.2018.0028
- Views 65
- Downloads 0
An exercise to sensitize undergraduate medical students about adverse drug reactions: An analysis
Introduction: Reporting of adverse drug reaction (ADR) is vital activity for the success of pharmacovigilance and healthcare professionals. The doctors play a pivotal role in the success of such activity. The one of the...
The study of antiepileptic activity of clove oil by MES model in mice
Background: The objective was to evaluate and compare the effect of extract of essential oil of clove with the standard sodium valproate on MES model. Methods: A total of thirty mice were taken, they were given an electr...
Mechanisms, Methods of Detection and Causality Assessment of Adverse Drug Reactions
Adverse Drug Reactions are very common cause of hospital morbidity
Study on Antinociceptive effect of Antihistaminics in albino mice
Objectives: To study the antinociceptive effect of promethazine and cetrizine in albino mice and to compare its antinociceptive effect with the standard drug morphine. Lastly to rule out the influence of sedation contrib...
Seroprevelance of common transfusion transmitted infection among the blood donors
Blood donation is responsible for saving large number of lives but associated with the risk of transfusion-transmissible infections (TTIs). Screening of TTIs among blood donors can be a cost-effective approach to monitor...