NEW INSIGHTS IN TO SYSTEMIC AMYLOIDOSIS: PRIMARY AMYLOIDOSIS ASSOCIATED WITH TUBERCULAR LYMPHADENITIS
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2014, Vol 3, Issue 4
Abstract
Tuberculosis is generally followed by secondary amyloidosis. The association of primary systemic amyloidosis with tuberculosis is very rare. There is only one case thus far reported in literature. We report such a rare case of primary amyloidosis with tuberculous lymphadenopathy. A 45 year old woman presented at the medicine department of all India institute of medical sciences , New Delhi with on & off erythematous rashes over both eyes for 1 year; low grade fever, fatigue and significant weight loss for 4 months, dysphagia for solid food since 1 month. Main finding on examination were pallor, macroglossia, bilateral periorbital erythematous rashes (racoon eyes), hepatomegaly & cardiomegaly. She had raised serum alkaline phosphatase level. Chest x-ray revealed cardiomegaly. USG abdomen revealed multiple retroperitoneal mesenteric lymph nodes and hepatomegaly. USG guided FNAC from mesenteric lymph node showed acid fast bacillus. Histological examination of liver biopsy showed amyloid deposition on congo red stain. Patient was treated with DOTS category I ATT with Bortezomib and Dexamethasone based weekly chemotherapy.
Authors and Affiliations
Shivraj Meena| Senior Resident, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India, Corresponding author email: shivraj.aiims@gmail.com, Nirmal Ghati| Junior Resident, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India, Rita Sood| Professor, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India, Naval Kishore Vikram| Additional Professor, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Keywords
Related Articles
- EP ID EP11289
- DOI 10.5958/2319-5886.2014.00054.x
- Views 227
- Downloads 14
ANALGESIC EFFICACY OF PARACETAMOL WHEN USED AS ADJUVANT IN IVRA
Introduction: Intravenous regional anaesthesia (IVRA) or Bier’s block is easy to administer, reliable, and cost-effective for short operative procedures of the extremities performed on an ambulatory basis where a loc...
Caffeine Consumption among Medical Interns and Association with GPA in Makkah Region
The Vagarious amount of caffeine may become harmful in frequent use, it increased among medical interns in Makkah region. The caffeine becomes a daily routine for medical interns without attention for their side harmful...
EVALUATION OF RECEPTIVITY OF THE MEDICAL STUDENTS IN A LECTURE OF A LARGE GROUP
Background: Lecturing is widely used teaching method in higher education. Instructors of large classes may have only option to deliver lecture to convey informations to large group students.Aims and Objectives: The pre...
Developing a Teacher Evaluation Model: The Impact of Teachers’ Attitude toward the Performance Evaluation System (PES) on Job Satisfaction and Organizational Commitment with the Mediating Role of Teachers’ Sense of Efficacy
The objective of this paper was to design, develop and evaluate a causal model of teachers’ attitude toward the performance evaluation system (PES) with the mediating role of teachers’ sense of efficacy on job satis...
Peak Exercise Response to Vertical Climbing in Chronic Obstructive Pulmonary Disease Patients
Background: Stair climbing is an integral component of daily living, which is limited in COPD. To date, stair climbing is used for prediction of VO2Max, pulmonary function, and postoperative complications. The study is...