New insights into the pathophysiology of nonalcoholic fatty liver disease
Journal Title: Annals of Hepatology - Year 2009, Vol 8, Issue 1
Abstract
The consequences of pathologic adipose tissue accumulation have been described for almost all organs. Nonalcoholic fatty liver disease (NAFLD) is considered the most relevant hepatic manifestation of obesity. There is great interest in the study of NAFLD, and new insights into its pathogenic process have been described. Currently, in addition to insulin resistance, which was considered the hallmark of this disease, endocrine, immunologic, and central nervous system factors are attracting interest as explanatory variables. In this review, new factors associated with the main theories on the pathophysiology of NAFLD are analyzed.
Authors and Affiliations
Norberto Chávez-Tapia, Misael Uribe, Guadalupe Ponciano-Rodríguez, Roberto Medina-Santillán, Nahum Méndez-Sánchez
Keywords
Related Articles
- EP ID EP77838
- DOI -
- Views 141
- Downloads 0
SVR24 rates in patients with HCV genotype 5 and 6 infection treated with peginterferon alfa-2a (40KD) plus ribavirin: results from the real world PROPHESYS study
Distribution of HCV genotypes and HCV RNA viral load in different regions of Mexico
Background and aim. To identify the geographic distribution of hepatitis C virus (HCV) genotypes and HCV RNA viral load in a large number of HCV-infected carriers in Mexico. Methods. Patients with chronic hepatitis C (n...
Hepatitis B virus prevalence and vaccination response in health care workers and students at the Federal University of Bahia, Brazil
Background and rationale for the study. Hepatitis B (HB) is one of the most prevalent occupational infections in health attendance environments. According to the Brazil Ministry of Health, health professionals must be va...
Antiviral therapy in patients with HCV-cirrhosis
The main cause of liver cirrhosis and liver cancer in the western world is Hepatitis C virus (HCV) infection. Liver transplantation is the only effective treatment once the disease is decompensated. In viremic patients w...
Protective role of standardized Feronia limonia stem bark methanolic extract against carbon tetrachloride induced hepatotoxicity
Objective. This study evaluates hepatoprotective potential of Feronia limonia stem bark (FSB) extracts and fractions using experimental models. Materials and methods. Activity levels of aspartate aminotransferase (AST) a...