New Onset Seizures in Young Adults in Coimbatore Medical College Hospital
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 2
Abstract
Backgroung & Objectives: Seizures are the one of the common medical disorder encountered in daily medical practice. In developing countries like India, CNS infections like meningitis, tuberculosis, HIV, malaria, cerebrovascular accident contribute significant number of cases. These CNS infections are having variable regional distribution. Etiology of seizures varies in developing countries in compared with developed countries. Hence this study was conducted to analyze the various etiologies of new onset seizures in adults the age group of 18-40 years in this region. Methods:The present study was conducted in coimbatoremedical college hospital, coimbatore.100 cases of new onset seizures were selected as per the criteria which mentioned in the materials and methods. The etiology was determined by appropriate investigations and neuroimaging including cerebrospinal fluid examination if necessary. Results: Out of 100 patients 92% were acute symptomatic seizures. The seizure types were GTCS in 56% and focal seizures with or without cognitive dysfunction in 26%. Among 100 patients 56% were males, 44% were females. CNS infection was the leading cause of seizures which accounted for 30%, followed by Cerebrovascularaccidents (22%), miscellaneous (12%) and metabolic (10%). In 8% patients of seizures were idiopathic.Among CNS infection (n=30), majority of seizures were due to meningitis accounted for 43.33% (13), followed by meningoencephalitis 30% (9), cerebral malariae 6.67% (2), tuberculoma 13.3% (4) and neurocysticercosis 6.67% (2).Among cerebrovascular accidents(n=22), CVT accounted for 49.9% (11), Haemorrhage for 18.1% (4), Infarct 13.6% (3), SAH 9.1% (2) and SDH 9.1% (2). (CVT – 10 + Eclampsia)In metabolic seizures (n=10) 70% were because of hypoglycaemia (7). 20% of seizures were pregnancy related. Conclusion: This study analyzes the etiological spectrum of seizures in this part of the world is different from that described from developed countries and CNS infections account for a significant number of cases.
Authors and Affiliations
P. S. Ramesh, B. Gowrishankar, S. P. Kumaresan, R. Aswinth, Ashwinimetry . , S. Aravinda Kumar
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