New oral anticoagulants
Journal Title: Journal of Health Sciences and Medicine - Year 2019, Vol 2, Issue 1
Abstract
Oral anticoagulants are medications that have an important place in the prevention and treatment of thromboembolic events that can be seen in the course of many diseases today. Warfarin, vitamin K antagonists are the most commonly known and used oral anticoagulants. Drugs known as new oral anticoagulants have emerged due to the difficulties in treatment and follow-up with warfarin. New oral anticoagulants exhibit anticoagulant effects, disrupting the structure and function of some factors in the coagulation cascade. There are many advantages such as monitorisation requirement, constant dose use, patient compliance and ease of follow-up. Meta-analyzes of large studies with new oral anticoagulants have shown that they are non-inferior from warfarin in the prevention and treatment of thromboembolic events, and even superior in some cases. Due to the ease of use and advantages of these new agents, they have been rapidly spreading and taking place in the prevention and treatment of embolism and ischemic events. Therefore, the areas of use of these drugs, the location of treatment, follow-up, possible side effects and most importantly management of bleeding complications should be well known and applied.
The evaluation of antimicrobial resistance of Enterococcus faecalis and Enterococcus faecium strains isolated from clinical specimens
Aim: Enterococci are found in human flora and have quite low virulence. However, enterococci causenosocomial and community acquired infections, and in recent years there has been an increase in antibiotic resistance rate...
The prevalence of contrast nephropathy in patients undergoing percutaneous coronary intervention in acute coronary syndrome
Objective: Contrast nephropathy (KMN) is defined as an acute renal injury due to intravenous contrast agents applied in diagnostic or therapeutic interventions and is an important cause of hospitalization due to acute re...
Serum amphiregulin level and pancreatic adenocarcinoma relation in patients with chronic pancreatitis
Aim: We aimed in our study to determine serum amphiregulin level, which is an indicator of a malignancy, and to foresee pancreatic carcinoma in chronic pancreatitis. Material and Method: Forty-two patients who applied to...
The effect of intracameral dexamethasone used at the end of cataract surgery on macular edema in eyes with diabetic retinopathy
Aim: To evaluate the effect of intracameral dexamethasone on diabetic macular edema injected at the end of cataract surgery in patients with diabetic retinopathy. Material and Method: Thirty patients with diabetic retino...
Examining the effects of phytochemicals used in phytotherapy on public health
The use of herbal products in treatment or prevention of diseases has been on the rise as herbal products are considered safe. Particularly several phenolic components of herbal products are thought to cause metabolical...