NEWER ANTIPLATELET AGENTS IN CARDIOVASCULAR DISEASE
Journal Title: Hygeia:journal for drugs and medicines - Year 2015, Vol 7, Issue 2
Abstract
Plan: Antiplatelet drugs are the corner stone in the treatment of cardiovascular disease. They remain the main stay in preventing aberrant platelet activation in pathophysiological conditions like myocardial infarction, ischemia and stroke. Preface: According to consensus guidelines, early revascularization and intensive antiplatelet therapy are key to reducing the complication that arises from myocardial ischemia and the recurrence of cardiovascular events. The different anti-platelets are aspirin, clopidogrel, ticagrelor, elinogrel, ticlopidine. Effective antagonism of the P2Y12 platelet receptor is central to the treatment of acute coronary syndrome. Limitations in safety, efficacy and tolerability have precluded many of the antiplatelet inhibitors from use in patients. Unforeseen incidences of increased bleeding risk and recurrent arterial thrombosis observed in patients have hampered the development of superior next generation antiplatelet therapies. Outcome: The effective antiplatelet therapy is important for the acute and secondary prevention of cardiovascular disease. The newer antiplatelet agents will reduce the limitation of the current therapy.
Authors and Affiliations
Panayappan L
Keywords
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- EP ID EP358823
- DOI 10.15254/H.J.D.Med.7.2015.148
- Views 39
- Downloads 0
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