News and comments: Do aristolochic acids truly increase the occurrence of hepatocellular carcinoma?
Journal Title: Traditional Medicine Research - Year 2018, Vol 3, Issue 1
Abstract
Recently, Science Translational Medicine pointed out that 78% of the 98 hepatocellular carcinoma (HCC) samples from Taiwan, China, showed distinctive signatures of aristolochic acids (AAs) exposure. In addition, 47% of the HCC samples from mainland China, 29% from Southeast Asia, 13% from Korea, and 2.7% from Japan showed AA signatures, which is much higher than those in North America and Europe, by searching for the AAs signature in 1,400 HCC samples from around the world. Researchers have suggested that there is a distinct relationship between AAs and HCC occurrence in Asia. As soon as the news comes out, the medical community is immediately triggered. Does AAs truly cause the occurrence of HCC?
Authors and Affiliations
Editor Group of TMR, Xiong-Zhi Wu
Keywords
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