Nigerian HIV Positive Mother Tested Negative after Fifty-Four Months on HAART
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 5, Issue 9
Abstract
Background: There is currently no cure for HIV/AIDS infection. Antiretroviral treatment can suppress and delay AIDS-related illness for many years but cannot clear the virus completely. This case review includes an attempt to find explanation for the conversion of an HIV positive grand-multiparous woman to a negative status. Findings: The source of data was the patient’s case file and review of relevant literature. A 38 year old HIV positive grand-multiparous female trader was diagnosed on 12/08/2010. She was placed on HAART for four years but was found to have tested HIV negative when the routine retroviral test was performed on 08/04/2014. Her last delivery was on 12/04/12 and she was placed on PMTCT regimen for that pregnancy. The baby’s status was not documented. From 16/08/2010 to 06/03/2014, the patient’s weight ranged between 52kg to 66kg. She was not screened for tuberculosis and viral load was not done. Initial CD4 count on 30/08/2014 was 357 cells / micro-liter while the value was 887 cells / micro-liter on the 24/02/2014. Other test results were essentially normal. Conclusions: Though a functional cure is a possibility here yet in resource limited settings, the lack of routine confirmatory testing, compounded by incorrect interpretation of weak positive test lines and use of tie breaker algorithms can leave a false-positive result undetected for a long time. Beyond HIV screening, mandatory confirmatory tests are imperative before reporting HIV positive results. Weak positive results should not be recognized as valid except in the screening of blood donors.
Authors and Affiliations
Prosper O. U. Adogu, Kenechukwu C. Okonkwo, Obiageli F. Emelumadu, Chioma A. Ofunnu, Amobi L. Ilika
Keywords
Related Articles
- EP ID EP347542
- DOI 10.9734/BJMMR/2015/13116
- Views 85
- Downloads 0
Predictors of Positive Outcomes in Pulmonary Rehabilitation
Aims: The study aims were to (1) determine the effect of participation in pulmonary rehabilitation on quality of life, severity of dyspnea, and exercise tolerance (2) evaluate predictors (number of pulmonary rehabilitat...
Parent’s Adiposity, Better Predicts Their Child’s Adiposity than Socio-economic Status in a Sample of 2689 Children Aged 8 to 15 Year in Urban Area in Cameroon: A Pilot Study
Background: Cameroon, as many Sub-Saharan African countries, is undergoing epidemiological transition. Parents as well as well their children are getting overweight and obese, mainly in large cities. Aims: This was a pil...
Prolactin Levels in Brazilian Patients Evaluated Because of Weight Gain: A Correlation with the Anthropometric and Biochemical Profiles?
Aims: To investigate if basal measures of serum prolactin correlate with biochemical and anthropometric data of Brazilian patients. Methodology: This study consists of a cross-sectional evaluation of basal serum prolac...
Knee Injuries: A Burden of Schoolboy Rugby Players
Background: School rugby injuries are a great concern to all rugby loving nations. There have been anecdotal reports by sport medical professionals that deviant quadriceps angle are associated with rugby knee injuries. T...
Sero-negative Antibody Status in HIV-Infected Children Initiated on Early Anti-Retroviral Therapy in Jos, Nigeria
Aim: To determine the association between the age at initiation of anti-retroviral therapy (ART) and the 18 month antibody status of human immunodeficiency virus (HIV)-infected children in Jos, Nigeria. Study Design: Thi...