Nitric Oxide Level Estimation in Patients of Oral Lichen Planus in Kashmiri Population – An Original Research
Journal Title: Indian Journal of Dental Advancements - Year 2019, Vol 11, Issue 1
Abstract
Background: The role of stress oxidative indices has been introduced in many autoimmune and inflammatory diseases such as atopic dermatitis, psoriasis vulgaris, vitiligo, and dermal lichen planus. Oxidative stress and antioxidant defense mechanism may play an important role in the pathology of oral lichen planus (OLP). Aims and Objectives: This study aims to evaluate the levels of nitric oxide (NO) in serum of patients with OLP and to compare the levels with the controls. Materials and Methods: The study included 30 cases of OLP patients which formed the study group and 30 cases of healthy individuals, which formed the controls. Results: The levels of NO were significantly higher in serum of cases with lichen planus than in normal. Conclusion: Serum NO was found to be higher in OLP patients which suggested that higher serum levels of NO in patients with OLP might activate the process of lymphocytes and cellular immunity system, hence, possibly endorsing the effect of serum NO in pathogenesis of lichen planus.
Authors and Affiliations
Altaf Hussain Chalkoo, Prenika Sharma, Nusrat Nazir Makroo
Keywords
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- EP ID EP600143
- DOI 10.5866/2019.11.10013
- Views 80
- Downloads 0
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