NMR Structure Elucidation of Natural Products and Synthesized Compounds in Nigeria
Journal Title: Tropical Journal of Natural Product Research - Year 2017, Vol 1, Issue 2
Abstract
Structure elucidation using Nuclear Magnetic Resonance Spectroscopy (NMR) is one of the greatest milestones of spectroscopy. NMR is matchless in the elucidation and confirmation of structures of organic compounds. The chemical shifts of the protons and carbons in the structure reveal a lot about chemical environments and reactivity as well as exploitable properties of the compounds. Although NMR has certain weaknesses such as poor sensitivity compared to mass spectrometry, UV and IR spectrophotometry, it is nevertheless most informative in terms of structure and chemical properties of compounds. NMR requires a high concentration of material for a good spectrum and even a higher concentration for the advanced experiments such as 2D COSY, TOCSY, HMBC, INADEQUATE, HSQC and NOESY.
Authors and Affiliations
John Igoli
Keywords
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- EP ID EP349872
- DOI 10.26538/tjnpr/v1i4.1
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