No evidence for activation of TH1 or TH17 pathways in unstimulated peripheral blood mononuclear cells from children with β-cell autoimmunity or T1D
Journal Title: Journal of Inflammation Research - Year , Vol 1, Issue
Abstract
The balance between TH1, TH2, TH17, and regulatory T cells has been suggested to be disturbed in type 1 diabetes (T1D). We investigated this balance in peripheral blood mononuclear cells (PBMC) from children at risk of developing T1D and children with T1D.
Authors and Affiliations
Jenny Walldén, Jarno Honkanen, Jorma Ilonen, Johnny Ludvigsson, Outi Vaarala
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Toll-like receptors (TLRs) represent a conserved family of innate immune recognition receptors. Among TLRs, TLR4 is important for the recognition of Gram-negative bacteria, whereas TLR2 recognizes cell wall constituents...
No evidence for activation of TH1 or TH17 pathways in unstimulated peripheral blood mononuclear cells from children with β-cell autoimmunity or T1D
The balance between TH1, TH2, TH17, and regulatory T cells has been suggested to be disturbed in type 1 diabetes (T1D). We investigated this balance in peripheral blood mononuclear cells (PBMC) from children at risk of d...
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