No increase in free fetal DNA level in ectopic pregnancy: A preliminary study
Journal Title: Turkish Journal of Obstetrics and Gynecology - Year 2017, Vol 14, Issue 3
Abstract
Objective: The aim of this study was to diagnose ectopic pregnancy in the early period by measuring cell-free fetal DNA (cffDNA) levels in maternal blood using spectrophotometry. Materials and Methods: Thirty patients with ectopic pregnancy and 30 patients with first trimester intrauterine pregnancy were enrolled in this prospective controlled study. cffDNA levels in maternal serum were measured using spectrophotometry. Results: There were no differences between the two groups in terms of cffDNA absorbance levels. Conclusion: Spectrophotometry is not suitable for measuring cffDNA levels to diagnose ectopic pregnancies in the early period. Practical and cost-effective methods should be found or larger patient series should be investigated.
Authors and Affiliations
Özge Kömürcü Karuserci, Mete Gürol Uğur, Özcan Balat, Seyhun Sucu
Keywords
Related Articles
- EP ID EP240924
- DOI 10.4274/tjod.54715
- Views 97
- Downloads 0
A comparison of emergency and therapeutic modified Shirodkar cerclage: an analysis of 38 consecutive cases
Objective: To compare the maternal and neonatal outcomes of patients with emergency versus therapeutic cerclage. Materials and Methods: The study included 38 female patients who underwent cervical cerclage using the modi...
Diagnostic value of neutrophil to lymphocyte ratio in differentiation of ruptured ovarian cysts and adnexal torsion
Objective: Ovarian cyst rupture and adnexal torsion (AT) differential diagnosis is important for early surgical intervention of AT for preserving ovarian function. The aim of this study was to evaluate the diagnostic val...
Prenatal diagnosis of persistent left superior vena cava: a retrospective study of associated congenital anomalies
Objective: To evaluate persistent left superior vena cava (PLSVC) cases according to associated cardiac, extracardiac, and chromosomal anomalies in the prenatal period and to review their outcomes. Materials and Methods:...
Subclinical hypothyroidism: Is it important in intracytoplasmic sperm injection cycles?
Objective: To compare intracytoplasmic sperm injection (ICSI) outcomes of women with subclinical hypothyroidism with those of euthyroid women. Materials and Methods: A retrospective case-control study was conducted. Out...
Is the measurement of the size of uterine lesions with positron emission tomography consistent in pre- and postmenopausal periods in endometrioid-type endometrial cancer?
Objective: We aimed to investigate the correlation of the size and volume of uterine tumors obtained using positron emission tomography/computed tomography (PET/CT) and pathology specimens in patients with endometrioid-t...