Nodular Melanoma Mimicking Keratoacanthoma Lessons to learn
Journal Title: Sultan Qaboos University Medical Journal - Year 2012, Vol 12, Issue 3
Abstract
A 67-year-old man of Chinese descent presented with a painless nodular lesion that had been present on his right forearm for the previous 3 months. A single, well-defned, dome-shaped, frm nodule with a central keratin plug surrounded by erythema was noted. Keratoacanthoma with secondary bacterial infection was suspected and the patient underwent an excision biopsy. Biopsy of the nodule and immunohistochemical staining supported a diagnosis of nodular malignant melanoma. It should be noted both that nodular malignant melanoma may present with a wide variety of clinical appearances, and that the lack of melanin pigment in nodular malignant melanoma may hinder the diagnosis of this aggressive tumour.
Authors and Affiliations
Leelavathi Muthupalaniappen| Departments of Family Medicine, Medical Faculty, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia, Srijit Das| Departments of Anatomy, Medical Faculty, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia, Norazirah Md Nor| Departments of Dermatology Unit, Medical Faculty, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia, Siti A. M. Ali| Departments of Pathology, Medical Faculty, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia
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