Non-Invasive Ventilation: First Line Therapy in the Acute Exacerbations of COPD in Emergency Department

Journal Title: Indian Journal of Emergency Medicine - Year 2017, Vol 3, Issue 2

Abstract

Noninvasive ventilation has been a major advancement in the management of acute exacerbations of chronic obstructive pulmonary disease. It reduces the need for endotracheal intubation, thereby reducing associated complications and hospital cost. The aim of our study is to assess the efficacy of noninvasive ventilation in acute exacerbations of chronic obstructive pulmonary disease with respiratory failure. A total of 86 patients presenting with acute respiratory distress at our emergency room were initially included and evaluated. Non invasive ventilation was initiated in addition to standard medical treatment in all cases. Response to therapy in terms of improvement in patients’ vitals and ABG were sequentially recorded and analyzed. Overall 72.5% (n=29) of the patients improved, whereas 27.5% (n=11) did not improve with NIV among whom 63.63% (n=7) had to be mechanically ventilated. 62.5% (n=25) showed a good ABG response with improvement in pH and decrease in PaCO2 levels. Therefore, NIV should be considered to be the first line of management in acute exacerbations of COPD with respiratory failure.

Authors and Affiliations

Mohammed Ismail Nizami

Keywords

Related Articles

Study of Acute Myocardial Infarction in Post Menopausal Women with Special Reference to Dyslipidemia

Introduction: Coronary artery disease is a leading cause of mortality among postmenopausal women in our country. It has been recognized that women are protected from CAD prior to the menopause. Statistics have showed tha...

Chronic Ulcerative Eyelid Lesion: A Rare Manifestation of Tuberculosis

Any organ system in the body can be affected by tuberculosis. While pulmonary tuberculosis is the most common presentation, extrapulmonary tuberculosis including ocular tuberculosis is also an important clinical problem....

A Rare Case Report of Toxic Myocarditis and Acute Kidney Injury in a Case of Phencyclidine and Unknown Poisoning

Phencyclidine (PCP, “angel dust”) is a hallucinogenic well known for its ability to induce disorganized thought processes, including euphoria, omnipotence, superhuman strength, and amnesia and dysphoria. It is an illicit...

Anticoagulant-Related Hemorrhagic Complication: A Rare Presentation

An anticoagulant is a drug (blood thinner) that treats, prevents, and reduces the risk of blood clots-breaking off and traveling to vital organs of the body, which can lead to life threatening situations. Anticoagulants...

Idiopathic Spontaneous Intraperitoneal Rupture of Bladder

Introduction: Intraperitoneal rupture of the bladder is considered rare(20%) as compared to extraperitoneal [1]. Idi-opathic rupture of urinary bladder is even rare (1%) [2]. The causes of spontaneous bladder rupture are...

Download PDF file
  • EP ID EP453286
  • DOI 10.21088/ijem.2395.311X.3217.7
  • Views 78
  • Downloads 0

How To Cite

Mohammed Ismail Nizami (2017). Non-Invasive Ventilation: First Line Therapy in the Acute Exacerbations of COPD in Emergency Department. Indian Journal of Emergency Medicine, 3(2), 217-222. https://europub.co.uk/articles/-A-453286