Non-osseous Tubercular Lesions of Spinal and Paraspinal Region-Evaluation by MRI
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 2
Abstract
ABSTRACT Introduction: Spinal tuberculosis is very common in developing countries like India and it has a wide spectrum of appearance on MRI ranging from simple marrow oedema to complete vertebral body collapse. Early diagnosis and intervention at initial period provide very good prognosis and very less morbidity. Aim: To demonstrate rare MRI features in cases of tubercular lesions in the spinal and paraspinal region without involvement of osseous components of the spine. Materials and Methods: This was a prospective descriptive study conducted in a Tertiary Care Hospital in India from June 2011 to December 2014 based on the MRI findings in patients with Tuberculosis of Spinal and Paraspinal region. Total 529 cases of tubercular spinal lesions were diagnosed. Out of which only 43 patients showed only extraosseous spinal and paraspinal lesions, these were included in the study. Patients with involvement of bony components or typical MRI pictures such as involvement of intervertebral disc and adjacent vertebral bodies were not included in the study. The diagnosis was confirmed by cytology, histopathology, serology and corroborative findings. Results: Various extraosseous changes involving spinal and paraspinal components in case of tubercular lesions, such as 27 cases of Paraspinal soft tissue lesions (62.8%)-Abscesses and Granulation tissue, 10 cases of Extradural and Intradural soft tissue component (23.2%), 4 cases of arachnoiditis (9.3%), 2 cases of Intramedullary Tuberculoma (4.6%) and 1 case of Spinal Cord Abscess (2.3%) were observed and the observed findings were tabulated. Conclusion: On MRI, Spinal Tuberculosis may have wide spectrum of appearance. Involvement of soft tissue without affecting the spinal bony component is quite rare. Hence, the possibility of tuberculosis should be considered even when the bony components are spared. Timely diagnosis and intervention will reduce the morbidity and avoids the complications. MRI plays key role in follow-up of patients to assess the response to treatment.
Authors and Affiliations
Jaiganesh Sivalingam, Anil Kumar, Konduru Varadarajulu Rajasekhar
Association of Circulating Insulin-like Growth Factors and IGF Binding Protein with Early Cases of Cancer Cervix
ABSTRACT Introduction: Insulin-like Growth Factor (IGF) signaling pathway has important roles in regulating cellular proliferation, apoptosis, differentiation and transformation. IGF-axis is implicated in pathogenesis of...
Modelling the Health Economic Impact of Influenza Vaccination Strategies for High-Risk Children in Vietnam
ABSTRACT Introduction: In Vietnam, since 2011 a National Influenza Surveillance System in Vietnam has implemented Severe Acute Respiratory Infection (SARI) surveillance to assemble information and inform administrational...
Knot of Henry: Role in Tendon Transfer
The term “Master knot of Henry” refers to the site of cross connections between long (extrinsic) tendons of foot namely Flexor Digitorum Longus Tendon (FDLT) and Flexor Hallucis Longus Tendon (FHLT). This chiasmatic stru...
Inflammation and Outcome in Traumatic Brain Injury: Does Gender Effect on Survival and Prognosis?
Introduction: Traumatic Brain Injury (TBI) accounts for the majority of trauma deaths and there has been increased interest in the understanding the role of prognostic factors. C-Reactive Protein (CRP) level increases ra...
Ultrasound Guided Oblique Subcostal Transverse Abdominis Plane Block using Local Anaesthetic Versus Saline for Laparoscopic Cholecystectomies: A Randomised Controlled Trial
ABSTRACT Introduction: Laparoscopic cholecystectomy surgery causes patients to have postoperative discomfort due to pain caused by incisions on the anterior abdominal wall. With the introduction of peripheral nerve block...