Non-targeted screening of emerging contaminants in drinking water based on high-resolution mass spectrometry
Journal Title: Shanghai Journal of Preventive Medicine - Year 2023, Vol 35, Issue 12
Abstract
ObjectiveTo establish a non-targeted screening method for emerging contaminants in drinking water based on high-resolution mass spectrometry and apply it to actual water samples.MethodsA total of 9 drinking water samples collected from 3 reservoirs in Shanghai were purified and concentrated by HLB solid phase extraction columnï¼ then separated and analyzed by liquid chromatography high-resolution mass spectrometer and gas chromatography highâresolution mass spectrometer. The acquired data were analyzed by Thermo Tracefinderï¼ Excel and other software combined with mzCloud and NIST databases. The methodology was verified with representative compound standards. Pesticide and perfluorinated compounds were taken as examples to analyze their pollution status.ResultsA non-targeted analysis strategy based on liquid chromatography and gas chromatography tandem high-resolution mass spectrometry was established. The pollution level of 20 kinds of pesticides and 4 kinds of perfluorinated compounds identified in 9 drinking water samples were higher in the Huangpu River than in the Yangtze River estuary.ConclusionThe established non-targeted screening method by high-resolution mass spectrometry can detect potential emerging contaminants in drinking water without relying on the standardsï¼ which provides a powerful technical means for water quality monitoring and risk assessment.
Authors and Affiliations
WU Linying,FENG Chao,WANG Guoquan,XUAN Dongliang,JIN Yuâe,PENG Qian,LU Dasheng,
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