“Non-traumatic vertebral body compression fracture in a young patient on antiepileptic treatment: A rare case report”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Background: Non traumatic compression fracture are normally seen in old and osteoporotic patient but rarely seen in young adult. We are presenting a rare case of a-traumatic thoracic vertebral body fracture in a young adult on antiepileptic treatment. Case characteristic: A 24 Years old male patient presented to us with chief complain of backache for 2 months. He was taking antiepileptic for last 6 month. There was no history of any other significant illness or trauma. On examination, mild localized tenderness with minimal round kyphosis over dorsal spine was present. On radiological evaluation, there was mild collapse of D5 and D9 vertebrae with T2 signal changes of adjacent vertebrae suggestive of osteoporotic compression fracture. Bone mineral density was less and both T and Z score were -1.9. Outcome: Patient was advised to stop antiepileptic drugs and bisphosphonate along with calcium and vitamin D3 were prescribed simultaneously resulted incomplete relief of pain as well his BMD was also improved after 2 month of therapy. Osteoporosis and loss of bone mass is known side effect of long term antiepileptic treatment but decrease in bone mineral density leading to non-traumatic vertebral body fracture in a short course (only 6 month) of antiepileptic therapy had not been document in literature. Conclusion: Regular screening for bone mineral density along with supplementation of bisphosphonate, calcium and vitamin D to maintain bone health should be done in all patients with antiepileptic treatment even for short course.
Authors and Affiliations
Dr Samrat smrutiranjan Sahoo, Dr Vinay Prabhat, Dr Gurudip Das, Dr Doki Sunil Kumar
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