Noninvasive ventilation in cancer children with acute respiratory failure
Journal Title: Journal of Acute Disease - Year 2017, Vol 6, Issue 1
Abstract
Objective: To establish the effectiveness of noninvasive ventilation in cancer children with acute respiratory failure. Methods: The data of 33 cancer patients were obtained prospectively from six different pediatric intensive care units in Turkey between the years of 2012 and 2013. Results: The diagnosis was leukemias in 25 (75.8%), lymphomas in 3 (9.1%) and other solid tumors in 5 (15.1%) patients. Pneumonia in 12 (36.3%) and sepsis in 15 (45.4%) patients were seen as the common reasons of respiratory failure. The mean PaO2/FiO2 ratios were (164.22 ± 37.24) and (126.80 ± 42.73) in noninvasive ventilation success and failure group, respectively. Noninvasive ventilation was successful in 18 (54.5%) patients. The failure group consisted of 15 patients required intubation. A total of 14 (42.4%) patients died. The clinical outcome in terms of success and failure was meaningful statistically (P = 0.0 00 1). Conclusions: Our results could encourage the use of noninvasive ventilation in children with cancer who develop acute respiratory failure. It should be considered as a useful therapeutic approach to avoid endotracheal intubation.
Authors and Affiliations
Sema Yilmaz, Riza Dincer Yildizdas, Oguz Dursun, Bulent Karapinar, Tanil Kendirli, Demet Demirkol, Agop Citak, Alphan Kupesiz, Hakan Tekguc, Muhterem Duyu, Pinar Yazici, Ufuk Yukselmis, Caglar Odek
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