NOVEL FURAN DERIVATIVES FROM 1-(4-CHLOROPHENYL)-3-(FURAN-2-YL)PROP-2-EN-1-ONE THROUGH ADDITION AND RING CLOSURE REACTIONS
Journal Title: BULETINUL INSTITUTULUI POLITEHNIC DIN IASI, CHIMIE SI INGINERIE CHIMICA - Year 2016, Vol 62, Issue 3
Abstract
Starting from a furan-containing chalcone analogue, a series of furan derivatives have been prepared. Addition of 4-chlorothiophenol to this chalcone analogue afforded the corresponding β-arylmercapto ketone, which has been subsequently reduced to the β-arylmercapto alcohol. The Stetter reaction of chalcone analogue with benzaldehyde and thiophene-2-carboxaldehyde gave two hitherto unknown butane-1,4-diones. Hydrazine and phenylhydrazine converted the chalcone analogue into the expected pyrazolines.
Authors and Affiliations
GHEORGHE ROMAN
Keywords
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