NOVEL FURAN DERIVATIVES FROM 1-(4-CHLOROPHENYL)-3-(FURAN-2-YL)PROP-2-EN-1-ONE THROUGH ADDITION AND RING CLOSURE REACTIONS

Abstract

Starting from a furan-containing chalcone analogue, a series of furan derivatives have been prepared. Addition of 4-chlorothiophenol to this chalcone analogue afforded the corresponding β-arylmercapto ketone, which has been subsequently reduced to the β-arylmercapto alcohol. The Stetter reaction of chalcone analogue with benzaldehyde and thiophene-2-carboxaldehyde gave two hitherto unknown butane-1,4-diones. Hydrazine and phenylhydrazine converted the chalcone analogue into the expected pyrazolines.

Authors and Affiliations

GHEORGHE ROMAN

Keywords

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  • EP ID EP201464
  • DOI -
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How To Cite

GHEORGHE ROMAN (2016). NOVEL FURAN DERIVATIVES FROM 1-(4-CHLOROPHENYL)-3-(FURAN-2-YL)PROP-2-EN-1-ONE THROUGH ADDITION AND RING CLOSURE REACTIONS. BULETINUL INSTITUTULUI POLITEHNIC DIN IASI, CHIMIE SI INGINERIE CHIMICA, 62(3), 21-31. https://europub.co.uk/articles/-A-201464