Abstract

Abstract A niosome is a non-ionic surfactant-based liposome. Niosomes are formed mostly by cholesterol incorporation as an excipient and having more penetrating characteristic than the previous preparations of emulsions. Niosomes and liposomes are bioequivalent in drug delivery systems, the potentiality to drug efficacy as compared with that of free drug. Niosomes are preferred over liposomes because the former exhibit high chemical stability and these are biodegradable, biocompatible nonimmunogenic and exhibit flexibility in their structural characterization. Niosomes have been widely evaluated for controlled release and targeted delivery for the treatment of immunological diseases. The review representing that encapsulation of drug in vesicular system can be predicted to prolong the existence of drug in the systemic circulation and enhance penetration into target tissue and reduce toxicity in a state of art technologies.

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