NS1 antigen: A new beam of light in the early diagnosis of dengue infection
Journal Title: Asian Pacific Journal of Tropical Medicine - Year 2016, Vol 9, Issue 12
Abstract
Objective: To evaluate NS1 antigen detection ELISA for the early laboratory diagnosis of dengue virus infection. Methods: The present study was conducted to evaluate the overall positivity of NS1 antigen detection ELISA and its comparison with viral RNA detection via real time PCR and IgM antibodies detection by ELISA. Results: A total of 1270 serum samples were tested 86% (1097/1270) were detected positive by one or more than one diagnostic test. Out of 1 270, 64% (807/1270) were positive by NS1 ELISA and 52% (662/1270), 51% (646/1270) were positive by real-time RT-PCR and IgM ELISA respectively. Conclusions: NS1 antigen detection ELISA is highly suitable diagnostic tools and it also has great value for use in outbreak and epidemic situation.
Authors and Affiliations
Muhammad Suleman, Syed Sohail Zahoor Zaidi
Keywords
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- EP ID EP281543
- DOI 10.1016/j.apjtm.2016.10.007
- Views 61
- Downloads 0
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