Abstract

As per WHO, Obesity is abnormal or excessive fat accumulation that may impair health. Women are more obese than the men in Gujarat State. Between the age of 15-49 years, 23.7% Women and 19.7% Men are overweight or obese (BMI ≥ 25.0 kg/m2) as per National Family Health Survey - 4, 2016 -17. Obesity leads to Diabetes mellitus, hypertension, and dyslipidemia. There are two major factors (i) Environmental (ii) Genetic, enhance the blood lipid levels. Basic Pathophysiology of obesity indicates insufficiency of Leptin, Ghrelin Hormones or insufficiency of Leptin, Ghrelin the receptors. Current Drug Treatment includes statins, bile acid sequestrants, ezetimibe that have side effects like rhabdomyolysis, muscle complaints, gastrointestinal disturbances, myalgia. Recent targets of the obesity are Amylin analogues, leptin analogues, GLP-1 analogues, Neuropeptide Y antagonists etc., which affects the hormonal balance into the body. Herbal Drugs are same effective as Current treatment, with no significant side effects. They are easily available from the natural sources, bio-compatible, Eco-friendly in nature. Certain edible mulberries, algaes, are the recent herbal sources for the treatment of the obesity. Key words: Obesity, BMI, Rhabdomyolysis, Myalgia, Eco-Friendly, Edible mulberries, Algae.

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