Obesity Related Adipokine Resistin Molecular Actions and Clinical Significance in Breast Cancer
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 2
Abstract
Globally at present cancer and obesity are two greatest health concerns. Obesity and its metabolic complications have rapidly become major global health issues and are associated with increased risk for cancer, especially breast cancer in postmenopausal women.Adipose tissue is considered as a genuine endocrine organ secreting a variety of bioactive adipokines, such as resistin. Current evidence has shown that the constellation of obesity, insulin resistance and adipokines is connected with the risk and prognosis of postmenopausalbreast cancer.Current review Focus on improving understanding of the obesity related adipokine resistin molecular mechanisms and Clinical significance of underpinning major diseases such as breast cancer and obesity, in order to develop novel diagnostic and therapeutic strategies and thus contribute to lowering the global burden of disease significantly.
Authors and Affiliations
Mohan Reddy. N, Kalyan Kumar. Ch, Kaiser Jamil, Lakshmi Narasu. M
Keywords
Related Articles
- EP ID EP374663
- DOI -
- Views 53
- Downloads 0
Nipah infection- Dentists Perspective
Nipah virus infection is a newly emerged zoonosis (disease transmitted to humans from animals) affecting the south-east Asia. As dentists are one of the health care professionals who work very closely with patients, this...
Adverse Drug Reactions Experienced During Intensive Phase of Standardized Ambulatory Regimen of MDR-TB, A Cross Sectional Study
Abstract: Aim of our study was to determine the adverse drug reactions experienced by the patients during intensive phase of standardized category IV regimen of multi drug resistant tuberculosis (MDR-TB). All eligible pa...
A Study on Health Status of Adolescent Girls of Dongria Kondh Tribe
Abstract: Adolescent period ranges between 10-19 yrs of age. Orissa occupies a unique place in the tribal map of India for having the largest number of tribal communities and the state ranks 2nd in terms of tribal popul...
Ochronosis- The Role of Total Hip Replacement: A Case Report and Review of Literature
Alkaptonuria is a rare autosomal recessive, single-gene metabolic disease caused by the lack of the enzyme homogentisic acid oxidase and characterized by black pigmentation of cartilage and other connective tissues. 38 y...
Awareness of Emergency Contraception among Nursing Students
Overpopulation in India is the burning problem. It is a major cause of poverty, illiteracy, decrease economy growth, starvation, malnutrition, depletion natural resources. The maternal mortality due to unsafe abortions i...