Obesity Related Adipokine Resistin Molecular Actions and Clinical Significance in Breast Cancer
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 2
Abstract
Globally at present cancer and obesity are two greatest health concerns. Obesity and its metabolic complications have rapidly become major global health issues and are associated with increased risk for cancer, especially breast cancer in postmenopausal women.Adipose tissue is considered as a genuine endocrine organ secreting a variety of bioactive adipokines, such as resistin. Current evidence has shown that the constellation of obesity, insulin resistance and adipokines is connected with the risk and prognosis of postmenopausalbreast cancer.Current review Focus on improving understanding of the obesity related adipokine resistin molecular mechanisms and Clinical significance of underpinning major diseases such as breast cancer and obesity, in order to develop novel diagnostic and therapeutic strategies and thus contribute to lowering the global burden of disease significantly.
Authors and Affiliations
Mohan Reddy. N, Kalyan Kumar. Ch, Kaiser Jamil, Lakshmi Narasu. M
Keywords
Related Articles
- EP ID EP374663
- DOI -
- Views 55
- Downloads 0
A case report of erosive lichen planus of the oral mucosa
Oral lichen planus mostly affects middle-aged females. It is a chronic muco-cutaneous autoimmune disease and factors like psychological stress, systemic conditions or drugs are the possible etiological conditions. Varian...
Screening of Wound Healing Effect of Nifedipine in Wistar Albino Rats
Abstract: The effect of Nifedipine was studied in rats using incision wound model. Total 18 rats were divided in to three groups each of 6 rats. G-I Control, G-II-Nifedipine (2 mg/kg) and G-III- Nifedipine (4 mg/kg). 6 c...
Effect of Passive Smokers on Lung Function (Ventilatory) in Age Group of 20-60 Years Old in Jaipur
Tobacco smoking is known risk factor for the development of distressing breathlessness, chronic obstructive lung diseases, burger`s disease, CHD, emphysema etc. In India, smoking is becoming more and more popular among y...
Word Recognition Score in White Noise Test in Healthy listeners
The acoustic cues of the speech signals which are consisted of consonants and vowels are very important for speech perception in noisy competing situations. Since the perception in noise test is one of the valuable measu...
A Comparative Study of Arthroscopic ACL Reconstruction Using Single Bundle versus Double Bundle Technique
The present comparative study of arthroscopic ACL Reconstruction using single bundle versus Double bundle technique was performed in the Department of Orthopaedics and Sports Medicine at Kamineni Hospitals, L B Nagar, an...