Observation of Serum Uric Acid Levels in Hundred Cases of Essential Hypertension
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 4
Abstract
Introduction: An elevation in serum uric acid has been associated with an increased risk for the development of hypertension and 25% to 50% of hypertensive individuals are hyperuricemic.Methods:One hundred adults aged between 20-50 years were selected for the study and referred consecutively to the medical OPD of Sri VenkateswaraRamnarainRuia Government General Hospital, Tirupati.They were studied for Serum Uric acid levels.Normotensive controls (n = 100) were selected for the study and evaluated for clinical and laboratory data.Both males and females were included for the study. All subjects and controls had normal renal function (Renal biochemistry, USG Abdomen).Results:In the present study , serum uric acid in the study population and control varied from 3.0 to 8.2 mg/dl and 3.0 to 7.2 mg/dl respectively. Statistically significant higher values of serum uric acid were observed in study population compared to control group (p=0.02). Hyper uricemia was found in 30% (n=21) of the cases compared to only 4.4% (n=4) in controls and this difference was statistically significant (p=0.02). Conclusion: Serum uric acid is strongly associated with BP in new and recent onset primary hypertension. An elevated or high–normal serum uric acid value >5.5mg/dl (mean uric acid-5.7 in this study) in an adult being evaluated for hypertension strongly supports the presence of primary hypertension.
Authors and Affiliations
Dr. KatakamAnantha Kumari
Keywords
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- DOI 10.9790/0853-1804023337.
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