Occult Hepatitis C Virus Infection in Hemodialysis Patients; Single Center Study.
Journal Title: Electronic Physician - Year 2015, Vol 7, Issue 8
Abstract
A new form of hepatitis C virus infection, known as occult hepatitis C virus (HCV) infection, is characterized by the presence of HCV_RNA in the liver or peripheral blood mononuclear cells (PBMCs). However, no serological markers of infection occur and there is not as much damage to the liver damage as is produced by chronic hepatitis C. There is a high incidence of HCV infection among hemodialysis patients, there is significant concern about viral transmission. HCV infection is a major problem in hemodialysis (HD) units even though blood products are screened for anti-HCV antibodies and other precautions are taken. The aim of this study was to determine the prevalence of occult HCV infection in PBMC in chronic hemodialysis (CHD) patients in the dialysis unit at Theodor Bilharz Research Institute (TBRI) with HCV antibodies and HCV RNA negativity irrespective of their liver function tests.
Authors and Affiliations
Samya El-Shishtawy, Nevine Sherif, Emad Abdallh, Laila Kamel, Mohamed Shemis, Abdel Aziz Ali Saleem, Haitham Abdalla, Hesham Gamal El Din
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