Occupational exposure to lead and organophosphorus pesticides: effect on male reproductive health.
Journal Title: Revista Peruana de Medicina Experimental y Salud Publica - Year 2008, Vol 25, Issue 4
Abstract
Nowadays there is an increased occupational exposure to different pollutants such as heavy metals and pesticides, because of the significant growth in industrial, mining, and agriculture activities. Adverse effects on human health can be observed in the respiratory, renal, nervous, endocrine, and reproductive systems, being the latter quite susceptible to many physical and chemical agents generated by industrial or agricultural activities. These agents are present in some specific activities or in the environment. Evidence from toxicological, epidemiological, biochemical, and physicioligal studies shows that lead has adverse effects on health of workers exposed to different concentrations of this metal, and the exposure may lead to male infertility. These negative effects include: libido reduction, impaired spermatogenesis (reduction in sperm number and motility, and increased number of abnormal sperm), chromosomal damage, abnormal prostate function, and changes in testosterone levels. In the case of organophosphorus pesticides (OPs), agriculture workers are at high risk for occupational and non-occupational exposure to these chemicals, because of their extensive use in agriculture and the household environment. OPs have been proven also to affect male reproductive system because of testicular toxicity leading to cytotoxic and cytokinetic reversible alterations in germinal cells, alterating androgen synthesis and quality of semen in exposed persons, particularly those individuals working in agriculture. This review focuses on the adverse effects on male reproductive function caused by occupational exposure to lead and organophosphorus compounds.
Authors and Affiliations
Sandra Yucra, Manuel Gasco, Julio Rubio, Gustavo Gonzales
Keywords
Related Articles
- EP ID EP91527
- DOI -
- Views 99
- Downloads 0
Effect of polivalent bothropic antivenom on phospholipase a2, l- amino acid oxidase and hyaluronidase from peruvian snake venom.
[i]Bothrops[/i] sp. snakes causing the largest number of cases of ophidism in Peru, their venom contain several enzymes related to poison spreading, miotoxic and platelet aggregation disturbances. [b][i]Objectives[/i][/b...
Semblanza de George Gordon Graham Gómez de La Torre (1923 - 2007)
Características morfométricas, genéticas, alimenticias y vectoriales de Panstrongylus herreri procedentes de Jaén (Cajamarca) y Cajaruro Amazonas), Perú
[b][i]Objetivo. [/i][/b]Comparar las características morfológicas, alimenticias y genéticas de dos poblaciones de [i]Panstrongylus herreri[/i], de los distritos de Jaén (Cajamarca) y Cajaruro (Amazonas). [b][i]Materiales...
Manejo institucionalizado del paciente con tuberculosis.
El manejo del paciente con tuberculosis (TB) a nivel institucional, que garantice la disminución del riesgo de transmisión, una adecuada vigilancia al tratamiento, y optar por medidas de soporte social, esta convirtiéndo...
Lead intoxication and other health problems in children population who live near mine mailing.
[b]Objectives. [/b]Determine levels of lead and other health problems in children under 10 years living in communities Quiulacocha and Champamarca, Pasco. [b]Materials and methods: [/b]Cross-sectional study conducted in...