Occurence of autoantibodies in healthy Omani individuals
Journal Title: Sultan Qaboos University Medical Journal - Year 2001, Vol 3, Issue 1
Abstract
Objectives: To investigate the occurence of various autoantibodies in the Omani population. Method: Sera from 392 healthy Omani individuals comprising 183 pregnant women and 209 blood donors (183 men and 26 women) were investigated. Autoantibodies were detected using immunofluorescence, haemagglutination and latex agglutination techniques. Result: Low levels of autoantibodies were detected in approximately 50% of the subjects; very few subjects showed high autoantibody titres. Anti smooth muscle autoantibodies (ASMA) were the most prevalent, and were detected in 31.6% of the individuals. Anti thyroid microsomal autoantibodies (ATMA) and anti thyro globulin autoantibodies (ATA) were present in 5.9% and 4.9% of indivi duals respect ively. The other autoantibodies were detected much less frequently, viz. anti nuclear auto antibodies (ANA) in 1.5%, anti parietal cells autoantibodies (APCA) in 1.8%, anti reticulin autoantibodies patterns (ARAP) in 3.0% and rheumatoid factor (RF) in 1.0% of the subjects. Conclusion: The data indicate that autoantibodies do exist in healthy Omani individuals and the results of clinical tests for these autoantibodies must be interpreted with caution.
Authors and Affiliations
Ali A. Al-Jabri| Department of Microbiology & Immunology, College of Medicine, Sultan Qaboos University, P.O. Box 35, Al-Khod 123, Muscat, Sultanate of Oman, Elizabeth R. Richens| Department of Microbiology & Immunology, College of Medicine, Sultan Qaboos University, P.O. Box 35, Al-Khod 123, Muscat, Sultanate of Oman
Keywords
Related Articles
- EP ID EP13623
- DOI -
- Views 359
- Downloads 18
Evaluation Tools in Postgraduate Medical Education Do we need “Made in Oman†tools?
Broad Ligament Lipoleiomyoma Masses Two curious cases masquerading as ovarian carcinomas
Lipoleiomyomas are an extremely rare form of uterine leiomyoma; moreover, the occurrence of this type of tumour on the broad ligament is even rarer. We report two cases of broad ligament lipoleiomyomas in 15- and 38-ye...
Perinatal Mortality Rate as a Quality Indicator of Healthcare in Al-Dakhiliyah Region, Oman
Objectives: Tis study aimed to provide insight into the causes of stillbirths and early neonatal deaths and identify better intervention strategies. Methods: Tis was a retrospective study during a 7-year period (January...
Re: Sodium Valproate-Induced Myopathy in a Child
Re: Stress in the Medical Profession and its Roots in Medical School