OCCURRENCE AND ANTIBIOGRAM OF IMIPENEM RESISTANT BACTERIA IN SACHET WATER SOLD IN CALABAR METROPOLIS, NIGERIA.
Journal Title: World Journal of Pharmaceutical and Medical Research - Year 2018, Vol 4, Issue 10
Abstract
Sachet water is an affordable drinking water which is widely consumed within the Calabar metropolis. The microbial quality of this drinking water is of outmost significance to public health and can contribute to failure in the use of carbapenems for treatment of bacterial infections especially among the neonates, aged and immunocompromised individuals. This study was undertaken to investigate the occurrence and antibiotics resistance profile of bacterial isolates from the vended sachet water samples. Ten different brands of sachet water from various manufacturers were randomly collected on different occassions and transported to the laboratory for analysis within 18h using the surface plating technique for isolation of bacteria. The isolates were subjected to imipenem susceptibility testing and susceptibility to other antibiotics following Clinical Laboratory Standard Institute (CLSI, 2009) guidelines. Eleven (22%) of the isolates were imipenem resistant, 24(48%) showed intermediate resistance and 15 (30%) were susceptible to imipenem. The species composition and frequency of isolation were: Salmonella spp (9%), Pseudomonas aeruginosa (6%), Aeromonas spp (20%), Proteus spp (10%), Citrobacter freundii (17%), Plesiomonas spp (3%), Serratia spp (6%), Enterobacter spp (17%), Acinetobacter spp, (3%), Klebsiella spp (9%). All the imipenem resistant isolates showed multiple resistance to the antibiotics except Citrobacter freundii which was resistant to only one antibiotic. The number of antibiotics other species showed resistance were Enterobacter spp (10 antibiotics), Acinetobacter spp (9 antibiotics), Plesiomonas spp (8 antibiotics), Pseudomonas aeruginosa (8 antibiotics), Salmonella spp (2 antibiotics), Proteus mirabilis (5 antibiotics), Serratia spp (5 antibiotics) and Klebsiella spp (4 antibiotics). The multiple antibiotics phenotype of these isolates is a threat to an effective therapy and may contribute to increased mortality and morbidity rates as well as other outcomes. Consequently, monitoring of the water quality of these vended sachet water should be given a top priority.
Authors and Affiliations
Archibong, C. P.
Keywords
Related Articles
- EP ID EP665720
- DOI -
- Views 177
- Downloads 0
DENTAL RADIOGRAPHY IN FORENSIC ODONTOLOGY
Teeth are the most indestructible part of the human body and are resistant to almost all environmental conditions like fire, desiccation, and decomposition. Hence teeth are the reliable source of forensic investigation....
ADVENT OF MAXILLOFACIAL PROSTHODONTICS FOR ORO-FACIAL DEFECTS
Maxillofacial prosthesis is that field of dentistry providing a replacement to surgical reconstruction of oral and facial defects. Oro-facial defects can lead to several psychosocial issues for the patient, making rehabi...
THE EFFECTS OF RAMADAN FASTING ON THE CHOLESTEROL AND TRIGLYCERIDE AMONGST HEALTHY SUDANESE IN KHARTOUM
Ramadan is known to be the holiest month of the Islamic calendar, during which millions of Muslims around the world fast the entire month and hence complying with one of the five pillars of Islam. During fasting Ramadan...
ADENOCARCINOMA OF FEMALE URETHRA TREATED BY CHEMORADIOTHERAPY – A CASE REPORT
Primary urethral adenocarcinoma of the female is rare. Its management is particularly challenging owing to the paucity of evidence from randomised trials to inform practice. We report a case of adenocarcinoma of the fema...
ETHNOVETERINARY PRACTICES- A REVIEW ON PHYTOTHERAPEUTICAL APPROACHES IN TREATMENT OF ANIMALS
Health and economy are the key features of our life. Livestock are the important part of our economy and therefore their health perspectives are equally important. Healthy animals yield healthy and nutritious products. B...