Occurrence of Metallo-Β-Lactmases Producing Pseudomonas aeruginosa among Clinical Isolates
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 2
Abstract
Abstract: Pseudomonas aeruginosa is an increasingly prevalent opportunistic human pathogen and the most common gram negative bacterium found in nosocomial infection. Production of metallo-β- lactamase enzyme in Pseudomonas aeruginosa usually results in high level resistance to most β-lactamases and a rapid spread of MBL producing major gram negative pathogens is a matter of particular concern worldwide. To identify the metallo –β-lactmase production by double disk synergy test, combined disk diffusion method and modified hodge test as described further. Out of 514 samples, on the basis of gram staining , 108(21.01%) gram positive cocci, 296(57.58%) gram negative bacilli, 89(17.31%) no organism seen and 21(4.08%) were yeast.On the basis of culture of 89 samples , 11 (12.35%) were gram positive cocci, 23 (25.84%) were gram negative bacilli, 55(61.81%) were showed no growth. In 319 samples of gram negative bacilli, 100 were isolates of Pseudomonas aeruginosa and in which 18 were found to be producing metallo β-lactmases. This study suggests metallo-beta-lactmase production in pseudomonas aeruginosa is emerging threat in hospital isolates because it is crucial for the optimal treatment of patients.
Authors and Affiliations
Divya Chaubey, Umar Farooq, Sudhir Singh
Keywords
Related Articles
- EP ID EP474022
- DOI -
- Views 61
- Downloads 0
Risk Factors Associated with Mortality of Low Birth Weight Neonates in Neonatal Intensive Care Unit of Misurata Teaching Hospital –Libya / 2015
Low birth weight by international agreement has been defined as a birth weight of less than 2500 grams. Birth weight is the single most important criterion for determining the neonatal and infant survival. Despite consis...
Factor Structure, Validity and Reliability of Job Behavior Assessment Scale (JBAS) of Physical Education Graduates
This present study describes the structure factors and examines the validity and reliability of a scale on the assessment of the job behaviour of Physical Education graduates who work for Fitness Clubs and Municipal Spor...
Association of Carotid Intimal Thickness with Fibrinogen & CRP in Diabetic Hypertensives
Diabetes and hypertension are two major diseases which account heavily for overall mortality and morbidity. Various associations have been studied between diabetes and hypertension with different markers to diagnose and...
Determinants and Complications of Pre-Labour Rupture of Membranes (PROM) At the University of Calabar Teaching Hospital (UCTH), Calabar, Nigeria
The management of pre-labour rupture of membranes (PROM) has been a challenging problem for decades in Obstetrics. The pregnancy complications are increased before term because of the increased risk of infection, preterm...
Analysis of scientific and ethical status of drug promotional literatures using WHO guidelines
The prime objective is to evaluate the scientific and ethical status of the drug promotional literatures (DPLs) available in Indian market using World Health Organization (WHO) criteria for ethical medicinal drug promoti...