OCT as a monitoring tool for assessment of the stage and severity of multiple sclerosis
Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 18, Issue 12
Abstract
AIM: To identify a link between optical coherence tomography(OCT), length of multiple sclerosis(MS)and the expanded disability status scale(EDSS).<p>METHODS: In a prospective double blind study, 29 patients with a diagnosis of MS were compared with 29 healthy patients, matched by age and sex. All participants underwent an OCT study and neurological EDSS test on the same day.<p>RESULTS: The mean EDSS score was 3.2 in the MS group <i>vs</i> 0.03 in the control group, and the duration of MS was 11.7y. The mean retinal nerve fiber layer(RNFL)thickness was significantly thinner in those with MS <i>(P</i><0.001). Correlation was found between duration of MS and RNFL thinning. EDSS and thinning of RNFL showed a tendency to correlate but without statistical significance.<p>CONCLUSION: RNFL is thinner in MS patients than in the general population. MS duration has a direct statistically significant effect on RNFL thickness. There seems to be a tendency of a relationship between RNFL thinning and EDSS. OCT is suggested as a monitoring and evaluation tool of MS patients.
Authors and Affiliations
Yoav Yechezkel Pikkel
Keywords
Related Articles
- EP ID EP484304
- DOI 10.3980/j.issn.1672-5123.2018.12.03
- Views 153
- Downloads 0
Fumigation treatment of Four Yellow Qing Ling Water with artificial tears for dry eyes
AIM: To observe the clinical efficacy of fumigation treatment of traditional Chinese medicine(Four Yellow Qing Ling Water)for dry eye, and to provide the reference for clinical treatment of dry eye. <p>METHODS: Totally 8...
Prevalence of myopia among primary and middle school students in Longkou City, Shandong Province
AIM: To investigate the prevalence of myopia among primary and middle school students aged 7 to 18 in Longkou City, Shandong Province, and to provide a scientific basis for prevention and control of myopia. <p>METHODS: T...
Comparison of posterior capsule folds following intracapsular implantation of three types of intraocular lenses with different haptic design
AIM: To compare the incidence of posterior capsule folds among different types of intraocular lens(IOL)to determine risk factors of posterior capsule folds. <p>METHODS:It was a retrospective study. We collected the cases...
Consistency of two eye anterior segment analysis systems measuring wave-front aberration before and after refractive surgery
AIM: To study the consistency of pre-operative and postoperative wave-front aberration between SCHWIND and SIRIUS eye anterior segment analysis system. <p>METHODS: Prospective control study. A total of 360 eyes of 180 pa...
Changes of corneal endothelial cells and tear film in patients with diabetic cataract after operation
AIM:To investigate the changes of corneal endothelial cells and tear film in diabetic cataract patients after operation. <p>METHODS: Totally 88 patients(88 eyes)with diabetic cataract(study group)treated in our hospital...