OCULAR ADNEXAL LYMPHOMAS- A CLINICOPATHOLOGIC AND HISTOMORPHOLOGIC ANALYSIS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 42
Abstract
BACKGROUND Ocular adnexal lymphomas are mainly Non-Hodgkin’s lymphomas distributed in the conjunctiva, orbit and eyelids. These lymphomas are the commonest of the ocular adnexal lymphoid proliferations. In this study, ten cases of ocular adnexal lymphomas were analysed over a three year period. MATERIALS AND METHODS Comparison of clinicopathologic and histomorphologic features was done in ten cases of ocular adnexal lymphomas Immunohistochemical confirmation was obtained in six cases. RESULTS Of ten cases, equal incidence (40% each) was found in conjunctiva and orbit with eyelid forming 20%. Most common presentation of intraocular lymphoma was found to be decreased vision with non-resolving uveitis. Orbital tumours presented as proptosis with visible conjunctival mass. The commonest histologic type of intraocular NHL is extra nodal marginal zone lymphoma (MALT lymphoma). Primary intraocular lymphomas are unilateral and 75% cases become bilateral with central nervous system involvement and death. CONCLUSION The present study is a retrospective analysis of ten cases of ocular adnexal lymphomas over a period of three years. Clinicopathologic and histomorphologic analysis was done in detail. Immunohistochemical confirmation was obtained in 6 cases.
Authors and Affiliations
Rema Priyadarsini, Priya V. S, Naina Jabeen Hyder
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