Ocular manifestations of rheumatic diseases: A hospital based study
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2016, Vol 2, Issue 3
Abstract
Abstract Background: Changes in the organ of sight in rheumatic diseases may result from the inflammatory process because of immune-mediated ocular inflammation which causes severe debilitation and visual loss. Therefore by understanding the various ocular presentations of these systemic inflammatory diseases is vital so as to arrive expeditiously at the correct diagnosis and treatment plan with the goal of preserving visual function. Methods: A cross sectional study was done on patients over a period from November 2014 to September 2015. A total of 102 patients with rheumatic disease were investigated for any ocular manifestations after obtaining informed written consent. ACR(American College of Rheumatology) criteria was used for the diagnosis of Rheumatic Diseases. Ocular investigation for dry eye included Schirmer’s test, Tear film break up time test (TBUT) and 1% Rose Bengal test. Positivity for Immunological factors and their association to ocular manifestations statistically analyzed. Results: The overall incidence of ocular manifestations of the rheumatic disease process in the study was 63.7% (65 cases). Uveitis incidence was 34.3%(35 cases) being the commonest ocular abnormality detected followed by KCS of 19.6%(20cases). The total number of cases with ANA positivity in Rheumatic disease is 22 as in Table 4, those with ocular manifestations and ANA positivity is 16 out of 20 (80%) as in Table 5. Six (50%) of the twelve patients with Keratoconjunctivitis sicca had high Rheumatoid factor titer values by slide agglutination (> 1:128). Conversely of the seven patients with high Rheumatoid factor titer values (> 1:128), six (85.7%) had Keratoconjunctivitis sicca. Conclusion: Therefore, following a multidisciplinary approach by ophthalmologists, rheumatologists, physicians and pediatrician would help for an early intervention to preserve vision where possible.
Authors and Affiliations
Kamran M Hassan, Manish S2, R. Ravikumar, R. Ravikumar, Syed Asghar Hussain
Keywords
Related Articles
- EP ID EP241424
- DOI -
- Views 107
- Downloads 0
Study of clinical significance of optical coherence tomography in diagnosis & management of diabetic macular edema
Abstract Background: 26 million people were estimated to be affected by diabetes in 2010 across the globe. Diabetic macular edema (DME) is the most important cause of visual impairment due to diabetic retinopathy. Optica...
Correlation of serum vitamin D level with the disease severity in vernal keratoconjunctivitis patients
Purpose Study aims to correlate serum vitamin D level to disease severity in children with vernal keratoconjunctivitisMaterials and Methods 50 patients in the age group between 515 years attending the out patient departm...
Comparison of postoperative cystoid macular edema in manual SICS vs phacoemulsification
Aim: To compare the macular edema occurring in patients postoperatively in uncomplicated manual SICS and uncomplicated phacoemulsification on the basis of macular thickness using optical coherence tomography (OCT). Setti...
Visual assessment in delayed development and cerebral palsy children in tertiary care center
Aim To assess vision in children with delayed development or cerebral palsy attending OPD at tertiary care hospital for early assessment and accurate detection of visual disorder which in turn helps their rehabilitation...
Glaucoma and diabetes: A review
Glaucoma is ranked second amongst the causes of irreversible blindness worldwide Diabetes mellitus DM is a global public health concern with numerous microvascular complications There is increasing evidence to suggest th...